It is of crucial importance to investigate the spatial structures of ancient landslides in the eastern Tibetan Plateau’s alpine canyons as they could provide valuable insights into the evolutionary history of the lan...It is of crucial importance to investigate the spatial structures of ancient landslides in the eastern Tibetan Plateau’s alpine canyons as they could provide valuable insights into the evolutionary history of the landslides and indicate the potential for future reactivation.This study examines the Deda ancient landslide,situated in the Chalong-ranbu fault zone,where creep deformation suggests a complex underground structure.By integrating remote sensing,field surveys,Audio-frequency Magnetotellurics(AMT),and Microtremor Survey Method(MSM)techniques,along with engineering geological drilling for validation,to uncover the landslide’s spatial feature s.The research indicates that a fault is developed in the upper part of the Deda ancient landslide,and the gully divides it into Deda landslide accumulation zoneⅠand Deda landslide accumulation zoneⅡin space.The distinctive geological characteristics detectable by MSM in the shallow subsurface and by AMT in deeper layers.The findings include the identification of two sliding zones in the Deda I landslide,the shallow sliding zone(DD-I-S1)depth is approximately 20 m,and the deep sliding zone(DD-I-S2)depth is 36.2-49.9 m.The sliding zone(DD-Ⅱ-S1)depth of the DedaⅡlandslide is 37.6-43.1 m.A novel MSM-based method for sliding zone identification is proposed,achieving less than 5%discrepancy in depth determination when compared with drilling data.These results provide a valuable reference for the spatial structural analysis of large-deepseated landslides in geologically complex regions like the eastern Tibetan Plateau.展开更多
由于文档纸张的几何形变、拍摄场景的干扰及拍摄角度不理想导致的透视失真,移动设备获取的文档图像的光学字符识别(Optical character recognition,OCR)性能受到很大挑战。针对折叠和扭曲的畸变文档图像预处理问题,设计了两种基于自编...由于文档纸张的几何形变、拍摄场景的干扰及拍摄角度不理想导致的透视失真,移动设备获取的文档图像的光学字符识别(Optical character recognition,OCR)性能受到很大挑战。针对折叠和扭曲的畸变文档图像预处理问题,设计了两种基于自编码器的网络结构,以实现自适应性图像矫正并提高文字识别正确率。首先提出空洞残差块和非对称卷积残差块两种残差块,然后将残差块与自编码器相结合,设计了一种非对称空洞自编码器网络;同时利用空间金字塔池化代替全连接层,并用非对称卷积残差块实现特征提取,设计了另一种空间金字塔自编码器网络。实验结果表明,与畸变图像相比,经非对称空洞自编码器网络矫正后的图像在OCR正确率、OCR召回率和文本相似度上分别提高了26.3%、20.4%和12.3%,而经空间金字塔自编码器网络矫正后的图像在正确率、召回率和文本相似度上分别提高了27.7%、22.0%和15.5%。与RectiNet等其他图像矫正网络相比,这两种网络可以自适应矫正多种类型的畸变文档图像,且矫正后的图像在文字识别上表现更为优异。本文提出的两种矫正网络能有效提高图像文字识别正确率、召回率和文本相似度,同时在鲁棒性、泛化性等方面与现有矫正网络相比具有明显的优势。展开更多
Esophageal squamous cell carcinoma(ESCC)is a malignant epithelial tumor,characterized by squamous cell differentiation,it is the sixth leading cause of cancer-related deaths globally.The increased mortality rate of ES...Esophageal squamous cell carcinoma(ESCC)is a malignant epithelial tumor,characterized by squamous cell differentiation,it is the sixth leading cause of cancer-related deaths globally.The increased mortality rate of ESCC patients is predominantly due to the advanced stage of the disease when discovered,coupled with higher risk of metastasis,which is an exceedingly malignant charac-teristic of cancer,frequently leading to a high mortality rate.Unfortunately,there is currently no specific and effective marker to predict and treat metastasis in ESCC.MicroRNAs(miRNAs)are a class of small non-coding RNA molecules,approximately 22 nucleotides in length.miRNAs are vital in modulating gene expression and serve pivotal regulatory roles in the occurrence,progression,and prognosis of cancer.Here,we have examined the literature to highlight the intimate correlations between miRNAs and ESCC metastasis,and show that ESCC metastasis is predominantly regulated or regulated by genetic and epigenetic factors.This review proposes a potential role for miRNAs as diagnostic and therapeutic biomarkers for metastasis in ESCC metastasis,with the ultimate aim of reducing the mortality rate among patients with ESCC.展开更多
基金supported by the National Natural Science Foundation of China(42372339)the China Geological Survey Project(DD20221816,DD20190319)。
文摘It is of crucial importance to investigate the spatial structures of ancient landslides in the eastern Tibetan Plateau’s alpine canyons as they could provide valuable insights into the evolutionary history of the landslides and indicate the potential for future reactivation.This study examines the Deda ancient landslide,situated in the Chalong-ranbu fault zone,where creep deformation suggests a complex underground structure.By integrating remote sensing,field surveys,Audio-frequency Magnetotellurics(AMT),and Microtremor Survey Method(MSM)techniques,along with engineering geological drilling for validation,to uncover the landslide’s spatial feature s.The research indicates that a fault is developed in the upper part of the Deda ancient landslide,and the gully divides it into Deda landslide accumulation zoneⅠand Deda landslide accumulation zoneⅡin space.The distinctive geological characteristics detectable by MSM in the shallow subsurface and by AMT in deeper layers.The findings include the identification of two sliding zones in the Deda I landslide,the shallow sliding zone(DD-I-S1)depth is approximately 20 m,and the deep sliding zone(DD-I-S2)depth is 36.2-49.9 m.The sliding zone(DD-Ⅱ-S1)depth of the DedaⅡlandslide is 37.6-43.1 m.A novel MSM-based method for sliding zone identification is proposed,achieving less than 5%discrepancy in depth determination when compared with drilling data.These results provide a valuable reference for the spatial structural analysis of large-deepseated landslides in geologically complex regions like the eastern Tibetan Plateau.
文摘由于文档纸张的几何形变、拍摄场景的干扰及拍摄角度不理想导致的透视失真,移动设备获取的文档图像的光学字符识别(Optical character recognition,OCR)性能受到很大挑战。针对折叠和扭曲的畸变文档图像预处理问题,设计了两种基于自编码器的网络结构,以实现自适应性图像矫正并提高文字识别正确率。首先提出空洞残差块和非对称卷积残差块两种残差块,然后将残差块与自编码器相结合,设计了一种非对称空洞自编码器网络;同时利用空间金字塔池化代替全连接层,并用非对称卷积残差块实现特征提取,设计了另一种空间金字塔自编码器网络。实验结果表明,与畸变图像相比,经非对称空洞自编码器网络矫正后的图像在OCR正确率、OCR召回率和文本相似度上分别提高了26.3%、20.4%和12.3%,而经空间金字塔自编码器网络矫正后的图像在正确率、召回率和文本相似度上分别提高了27.7%、22.0%和15.5%。与RectiNet等其他图像矫正网络相比,这两种网络可以自适应矫正多种类型的畸变文档图像,且矫正后的图像在文字识别上表现更为优异。本文提出的两种矫正网络能有效提高图像文字识别正确率、召回率和文本相似度,同时在鲁棒性、泛化性等方面与现有矫正网络相比具有明显的优势。
基金Supported by Foundation of Henan Educational Committee,No.22A310024and Natural Science Foundation for Young Teachers'Basic Research of Zhengzhou University,No.JC202035025。
文摘Esophageal squamous cell carcinoma(ESCC)is a malignant epithelial tumor,characterized by squamous cell differentiation,it is the sixth leading cause of cancer-related deaths globally.The increased mortality rate of ESCC patients is predominantly due to the advanced stage of the disease when discovered,coupled with higher risk of metastasis,which is an exceedingly malignant charac-teristic of cancer,frequently leading to a high mortality rate.Unfortunately,there is currently no specific and effective marker to predict and treat metastasis in ESCC.MicroRNAs(miRNAs)are a class of small non-coding RNA molecules,approximately 22 nucleotides in length.miRNAs are vital in modulating gene expression and serve pivotal regulatory roles in the occurrence,progression,and prognosis of cancer.Here,we have examined the literature to highlight the intimate correlations between miRNAs and ESCC metastasis,and show that ESCC metastasis is predominantly regulated or regulated by genetic and epigenetic factors.This review proposes a potential role for miRNAs as diagnostic and therapeutic biomarkers for metastasis in ESCC metastasis,with the ultimate aim of reducing the mortality rate among patients with ESCC.
