Idiopathic membranous nephropathy is a common primary glomerular disease.Recently,it has been found that the progression and prognosis of glomerular diseases are not only related to the glomeruli itself,but also to th...Idiopathic membranous nephropathy is a common primary glomerular disease.Recently,it has been found that the progression and prognosis of glomerular diseases are not only related to the glomeruli itself,but also to the severity of renal tubular injury.Although blood creatinine and urinary protein are recognized biomarkers,they appear late,are insensitive,lack specificity,and are difficult to respond to IMN conditions in a timely and accurate manner.Markers such as N-acetyl-β-D-glucosaminidase,kidney injury molecule 1,neutrophil gelatinase-associated lipoprotein in urine can dynamically reflect the progress of kidney injury in the early stage,and are detected as noninvasive,so It has been applied in IMN,but such research is lacking,and the scope needs to be further expanded and discussed in depth.展开更多
The global coronavirus disease 2019(COVID-19)pandemic has had a massive impact on global social and economic development and human health.By combining traditional Chinese medicine(TCM)with modern medicine,the Chinese ...The global coronavirus disease 2019(COVID-19)pandemic has had a massive impact on global social and economic development and human health.By combining traditional Chinese medicine(TCM)with modern medicine,the Chinese government has protected public health by supporting all phases of COVID-19 prevention and treatment,including community prevention,clinical treatment,control of disease progression,and promotion of recovery.Modern medicine focuses on viruses,while TCM focuses on differential diagnosis of patterns associated with viral infection of the body and recommends the use of TCM decoctions for differential treatment.This differential diagnosis and treatment approach,with its profoundly empirical nature and holistic view,endows TCM with an accessibility advantage and high application value for dealing with COVID-19.Here,we summarize the advantage of and evidence for TCM use in COVID-19 prevention and treatment to draw attention to the scientific value and accessibility advantage of TCM and to promote the use of TCM in response to public health emergencies.展开更多
基金Natural Science Foundation of Hebei Province(No.2019423037)Hebei Provincial Administration of Traditional Chinese Medicine(No.2020072)。
文摘Idiopathic membranous nephropathy is a common primary glomerular disease.Recently,it has been found that the progression and prognosis of glomerular diseases are not only related to the glomeruli itself,but also to the severity of renal tubular injury.Although blood creatinine and urinary protein are recognized biomarkers,they appear late,are insensitive,lack specificity,and are difficult to respond to IMN conditions in a timely and accurate manner.Markers such as N-acetyl-β-D-glucosaminidase,kidney injury molecule 1,neutrophil gelatinase-associated lipoprotein in urine can dynamically reflect the progress of kidney injury in the early stage,and are detected as noninvasive,so It has been applied in IMN,but such research is lacking,and the scope needs to be further expanded and discussed in depth.
基金The study was supported by the National Emergency Programs for Science and Technology Development(No.2021YFC0863200)the National Natural Science Foundation of China Youth Program(82004505)+1 种基金Tianjin Education Commission Research Program Project(No.2022KJ146)New Faculty Research Initiation Project of Tianjin University of Traditional Chinese Medicine(No.XJS2022113).
文摘The global coronavirus disease 2019(COVID-19)pandemic has had a massive impact on global social and economic development and human health.By combining traditional Chinese medicine(TCM)with modern medicine,the Chinese government has protected public health by supporting all phases of COVID-19 prevention and treatment,including community prevention,clinical treatment,control of disease progression,and promotion of recovery.Modern medicine focuses on viruses,while TCM focuses on differential diagnosis of patterns associated with viral infection of the body and recommends the use of TCM decoctions for differential treatment.This differential diagnosis and treatment approach,with its profoundly empirical nature and holistic view,endows TCM with an accessibility advantage and high application value for dealing with COVID-19.Here,we summarize the advantage of and evidence for TCM use in COVID-19 prevention and treatment to draw attention to the scientific value and accessibility advantage of TCM and to promote the use of TCM in response to public health emergencies.