Synthesis of CC/BiPO4/Bi2WO6 Composite Material and Its Photocatalytic Performance

Along with the popularity of environmental protection concepts, the environmental treatment of water pollution attracts widespread attention, among which, the research on Bi-based semiconductor photocatalytic degradation technology has made great progress. However, the development of such bismuth-based composites still remains a challenging task due to difficult recovery and low catalytic efficiency. Herein, a novel CC/BiPO4/Bi2WO6 composite was successfully synthesized through two-step hydrothermal method using activated flexible carbon cloth as a substrate. The results of the photocatalytic degradation experiments showed that the obtained CC/BiPO4/Bi2WO6 composites can degrade 92.1% RhB in 60 min under UV-visible light irradiation, which was much higher than that of unloaded BiPO4 (24.4%) and BiPO4/Bi2WO6 (52.9%), exhibiting a better adsorption-photocatalytic degradation performance than BiPO4 and BiPO4/Bi2WO6. Photoluminescence spectra indicated that the improved photocatalytic activity was due to the more effective inhibition of photogenerated carrier complexation. Furthermore, the radical capture experiments confirmed that h+, ·OH and O2- were the main active substances in the photocatalytic degradation process of RhB by the CC/BiPO4/Bi2WO6 composites. More importantly, the prepared CC/BiPO4/Bi2WO6 composite had a simple separation process and good recycling stability, and its photocatalytic degradation efficiency can still reach 53.3% after six cycles of RhB degradation. .

Different Dosages of Intravitreal Triamcinolone Acetonide Injections for Macular Edema Secondary to Central Retinal Vein Occlusion

Purpose:.To study the effect of intravitreal injections of triamcinolone acetonide (TA) for the treatment of macular edema secondary to central retinal vein occlusion.(CRVO).in a sample of Chinese patients from Shaanxi province. Methods:.The 50 eyes from 50 patients were separated into three TA treatment groups:.17 patients were given 4 mg/0.1 ml,.19 patients were given 8 mg/0.2 ml,.and 14 patients were given 16 mg/0.4 ml. Patients were followed up for 12 months. Foveal thickness, intraocular pressure (IOP), and best-corrected visual acuity (BCVA) were measured. Results:.Macular edema responded well both anatomically and functionally to the TA injections. After the initial intravitreal injection,.macular edema recurred at 2-4 months in the low-dose group.(4 mg),.at 3-5 months in the medium-dose group (8 mg), and at 6-9 months in the high-dose group (16 mg)..No significant difference in BCVA or in foveal thickness were observed between the first intravitreal injection and the re-injection. There was no increase in IOP after re-injection of 16 mg TA,.if the patient did not have an elevated IOP after the initial intravitreal injection of 4/8 mg TA. Conclusion: A low dosage of TA (4 mg) administered via intravitreal injection might be useful as an initial treatment for macular edema secondary to CRVO..A higher dosage of TA (16mg) can be used if there is no IOP elevation with the initial TA injection.

Triamcinolone Intravitreal Injection and Intraocular Pressure in Macular Edema Associated with Retinal Vein Occlusion

Purpose:To study the risk factors of increased intraocular pressure (IOP) response to triamcinolone acetonide intravitreal (IVTA) injection in eyes with macular edema associated with retinal vein occlusion. Methods:Eighty-nine eyes with macular edema associated with retinal vein occlusion first received periocular injection of 40 mg triamcinolone acetonide (TA) and were followed for one month. According to the diversity of IOP after periocular TA (PTA) injection, they were divided into the elevation IOP group (group A, 26 eyes) and the normal IOP group (group B,63 eyes).They then received 4 mg TA intravitreal injection.IOP measurements were recorded after PTA and IVTA injections, and were followed for six months. Results: Both PTA and IVTA injections caused a rise in IOP, but it was higher in the IVTA injection (40.45%) than in the PTA injection (29.21%). The mean rise in IOP was more significant in eyes with IVTA injection (28.08 ± 8.24 mmHg) than in eyes with PTA injection (20.87 ± 4.07 mmHg). Patients with an elevation IOP above 6 mmHg after PTA injection had a 73.08% chance of developing a pressure of 24 mmHg or higher,whereas only 12.70% of those with an elevation IOP below 6 mmHg after PTA injection experienced pressure elevation. Conclusion:IOP response to PTA injection is a good way to judge IOP response to IVTA. If the patient is highly sensitive to corticosteroid, treatments other than IVTA injection are used to avoid the increased risks associated with intravitreal corticosteroid injection.

SARS-CoV-2 immunity in animal models

The COVID-19 pandemic,which was caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has become a worldwide health crisis due to its transmissibility.SARS-CoV-2 infection results in severe respiratory illness and can lead to significant complications in affected individuals.These complications encompass symptoms such as coughing,respiratory distress,fever,infectious shock,acute respiratory distress syndrome(ARDS),and even multiple-organ failure.Animal models serve as crucial tools for investigating pathogenic mechanisms,immune responses,immune escape mechanisms,antiviral drug development,and vaccines against SARS-CoV-2.Currently,various animal models for SARS-CoV-2 infection,such as nonhuman primates(NHPs),ferrets,hamsters,and many different mouse models,have been developed.Each model possesses distinctive features and applications.In this review,we elucidate the immune response elicited by SARS-CoV-2 infection in patients and provide an overview of the characteristics of various animal models mainly used for SARS-CoV-2 infection,as well as the corresponding immune responses and applications of these models.A comparative analysis of transcriptomic alterations in the lungs from different animal models revealed that the K18-hACE2 and mouse-adapted virus mouse models exhibited the highest similarity with the deceased COVID-19 patients.Finally,we highlighted the current gaps in related research between animal model studies and clinical investigations,underscoring lingering scientific questions that demand further clarification.

Numerical simulation and analysis of the underwater implosion of spherical hollow ceramic pressure hulls in 11000 m depth

Pressure hulls play an important role in deep-sea underwater vehicles.However,in the ultra-high pressure environment,a highly destructive phenomenon could occur to them which is called implosion.To study the characteristics of the flow field of the underwater implosion of hollow ceramic pressure hulls,the compressible multiphase flow theory,direct numerical simulation,and adaptive mesh refinement are used to numerically simulate the underwater implosion of a single ceramic pressure hull and multiple linearly arranged ceramic pressure hulls.Firstly,the feasibility of the numerical simulation method is verified.Then,the results of the flow field of the underwater implosion of hollow ceramic pressure hulls in 11000 m depth is analyzed.There are the compression-rebound processes of the internal air cavity in the implosion.In the rebound stage,a shock wave that is several times the ambient pressure is generated outside the pressure hull,and the propagation speed is close to the speed of sound.The pressure peak of the shock wave has a negative exponential power function relationship with the distance to the center of the sphere.Finally,it is found that the obvious superimposed effect between spheres exists in the chain-reaction implosion which enhances the implosion shock wave.

Current research status of tumor cell biomarker detection

With the annual increases in the morbidity and mortality rates of tumors,the use of biomarkers for early diagnosis and real-time monitoring of tumor cells is of great importance.Biomarkers used for tumor cell detection in body fluids include circulating tumor cells,nucleic acids,protein markers,and extracellular vesicles.Among them,circulating tumor cells,circulating tumor DNA,and exosomes have high potential for the prediction,diagnosis,and prognosis of tumor diseases due to the large amount of valuable information on tumor characteristics and evolution;in addition,in situ monitoring of telomerase and miRNA in living cells has been the topic of extensive research to understand tumor development in real time.Various techniques,such as enzyme-linked immunosorbent assays,immunoblotting,and mass spectrometry,have been widely used for the detection of these markers.Among them,the detection of tumor cell markers in body fluids based on electrochemical biosensors and fluorescence signal analysis is highly preferred because of its high sensitivity,rapid detection and portable operation.Herein,we summarize recent research progress in the detection of tumor cell biomarkers in body fluids using electrochemical and fluorescence biosensors,outline the current research status of in situ fluorescence monitoring and the analysis of tumor markers in living cells,and discuss the technical challenges for their practical clinical application to provide a reference for the development of new tumor marker detection methods.

Stabilizing layered superlattice MoSe_(2)anodes by the rational solvation structure design for low-temperature aqueous zinc-ion batteries

Aqueous zinc-ion batteries(AZIBs)have attracted widespread attention due to their intrinsic merits of low cost and high safety.However,the poor thermodynamic stability of Zn metal in aqueous electrolytes inevitably cause Zn dendrites growth and interface parasitic side reactions,resulting in unsatisfactory cycling stability and low Zn utilization.Replacing Zn anode with intercalation-type anodes have emerged as a promising alternative strategy to overcome the above issues but the lack of appropriate anode materials is becoming the bottleneck.Herein,the interlayer structure of MoSe_(2)anode is preintercalated with long-chain polyvinyl pyrrolidone(PVP),constructing a periodically stacked p-MoSe_(2)superlattice to activate the reversible Zn^(2+)storage performance(203 mAh g^(−1)at 0.2 A g^(−1)).To further improve the stability of the superlattice structure during cycling,the electrolyte is also rationally designed by adding 1,4-Butyrolactone(γ-GBL)additive into 3 M Zn(CF_(3)SO_(3))_(2),in whichγ-GBL replaces the H2O in Zn^(2+)solvation sheath.The preferential solvation ofγ-GBL with Zn^(2+)effectively reduces the water activity and helps to achieve an ultra-long lifespan of 12,000 cycles for p-MoSe_(2).More importantly,the reconstructed solvation structure enables the operation of p-MoSe_(2)||ZnxNVPF(Na3V2(PO4)2O_(2)F)AZIBs at an ultra-low temperature of−40°C,which is expected to promote the practical applications of AZIBs.

妊娠期新冠患者的临床表现及其新生儿健康状况

2019年末,新型冠状病毒肺炎在全球开始蔓延,严重威胁孕产妇和新生儿生命安全,但目前对这类特殊人群的临床报道和研究还比较少.本文回顾性研究分析了武汉地区2020年1月21日~2月9日收治的五位新冠肺炎孕妇及其新生儿的临床表现和CT、血常规、病毒核酸等检查结果.结果显示,与普通新冠肺炎患者临床表现类似,患者均出现了发热、咳嗽、肺部CT磨玻璃状等新冠肺炎典型特征.在发病初期,患者均出现了淋巴细胞与嗜酸性粒细胞计数显著降低这一现象.五位患者均在住院期间通过顺产或剖腹产安全分娩,且新生儿在出生后10~33 d,核酸检测结果均为阴性.根据患者及其新生儿的临床表现与核酸检验结果,在这五例病例中未观察到新冠病毒的母婴垂直传播.此外,淋巴细胞减少、嗜酸性粒细胞减少,以及C反应蛋白升高这三项临床检验指标的变化特征,有可能帮助新冠肺炎孕产妇的早期诊断与筛查.

Synthesis of Co_(4)S_(3)/Co_(9)S_(8) nanosheets and comparison study toward the OER properties induced by different metal ion doping

Regulation of chemical composition and nanostructure, such as the introduction of dopant into two-dimensional nanomaterials, is a general and valid strategy for the efficient electrocatalyst design. In this work, Co_(4)S_(3)/Co_(9)S_(8) nanosheets, with an ultrathin layer structure, were successfully synthesized via an efficient solvothermal process combined with ultrasonic exfoliation. Different metal ions (M = Fe^(3+), Cr^(3+), Mn^(2+) and Ni^(2+)) were then doped by a simple cation exchange method and the effects of different dopants on the OER activities of Co_(4)S_(3)/Co_(9)S_(8) NS were further investigated in alkaline media. The corresponding results implied that M-doped Co_(4)S_(3)/Co_(9)S_(8) NS (M = Fe^(3+), Cr^(3+), Mn^(2+) and Ni^(2+)) exhibited different electrocatalytic properties. Evidenced by XPS spectra, the different OER activities were mainly aroused by the redistribution of charge at the interface due to an electronic interaction between the doped metal ions and Co_(4)S_(3)/Co_(9)S_(8) NS.

Observation of magnetic domain evolution in constrained epitaxial Ni–Mn–Ga thin films on MgO(0 0 1) substrate

Epitaxial Ni–Mn–Ga thin films have promising application potential in micro-electro-mechanical sensing and actuation systems. To date, large abrupt magnetization changes have been observed in some epitaxial Ni–Mn–Ga thin films, but their origin-either from magnetically induced martensite variant reorientation(MIR) or magnetic domain evolution-has been discussed controversially. In the present work, we investigated the evolutions of the magnetic domain and microstructure of a typical epitaxial Ni–Mn–Ga thin film through wide-field magneto-optical Kerr-microscopy. It is demonstrated that the abrupt magnetization changes in the hysteresis loops should be attributed to the magnetic domain evolution instead of the MIR.