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合成生物学时代基于非模式细菌的工业底盘细胞研究现状与展望 被引量:9
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作者 杨永富 耿碧男 +5 位作者 宋皓月 胡蜜蜜 何桥宁 陈守文 白凤武 杨世辉 《生物工程学报》 CAS CSCD 北大核心 2021年第3期874-910,共37页
工业微生物底盘细胞的开发将为工业生物技术的发展提供优良的细胞工厂,有利于实现环境保护及经济可持续发展。基于合成生物学"设计-构建-测试-学习"(Design-Build-Test-Learn,DBTL)策略,对底盘细胞进行多维度的理性或半理性... 工业微生物底盘细胞的开发将为工业生物技术的发展提供优良的细胞工厂,有利于实现环境保护及经济可持续发展。基于合成生物学"设计-构建-测试-学习"(Design-Build-Test-Learn,DBTL)策略,对底盘细胞进行多维度的理性或半理性改造是实现"建物致知"以及"建物致用"目标的重要手段。文中简述了合成生物学DBTL策略中各步骤相关的重要技术方法;概述了部分重要模式微生物底盘细胞的策略与研究进展;重点比较介绍了工业生物技术领域具有特殊生理功能、利用一碳化合物及高效生产平台化合物的部分非模式细菌;同时也提出了实现优良、安全合成微生物细胞工厂构建与应用的策略。这些方法策略包括依靠合成生物学技术方法,综合模式与非模式微生物优势,开发应用经济、高效的高通量智能装备,建立分子组学与表型组学研究平台,推动多层次系统生物学与表型组学大数据的解析、整合、模拟与可视化,以及建立高质量的数字细胞模型和基因组优化的底盘细胞,推动高效、优良工业细胞工厂的理性设计、构建与应用。 展开更多
关键词 合成生物学 工业微生物 底盘细胞 微生物细胞工厂 非模式微生物 生物安全
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Experiment study of a quartz tube falling particle receiver 被引量:5
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作者 Tianjian WANG fengwu bai +2 位作者 Shunzhou CHU Xiliang ZHANG Zhifeng WANG 《Frontiers in Energy》 SCIE CSCD 2017年第4期472-479,共8页
This paper presents an experimental evaluation of a specially designed falling particle receiver. A quartz tube was used in the design, with which the particles would not be blown away by wind. Concentrated solar radi... This paper presents an experimental evaluation of a specially designed falling particle receiver. A quartz tube was used in the design, with which the particles would not be blown away by wind. Concentrated solar radiation was absorbed and converted into thermal energy by the solid particles flowed inside the quartz tube. Several experiments were conducted to test the dynamic thermal performance of the receiver on solar furnace system. During the experiments, the maximum particle temperature rise is 212~C, with an efficiency of 61.2%, which shows a good thermal performance with a falling distance of 0.2 m in a small scale particle receiver. The average outlet particle temperature is affected by direct normal irradiance (DNI) and other factors such as wind speed. The solid particles obtain a larger viscosity with a higher temperature while smaller solid particles are easier to get stuck in the helix quartz tube. The heat capacity of the silicon carbide gets larger with the rise of particle temperature, because as the temperature of solid particles increases, the temperature rise of the silicon carbide decreases. 展开更多
关键词 solar thermal electricity central receiver particle receiver experimental research
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Optical performance analysis of an innovative linear focus secondary trough solar concentrating system
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作者 Xiliang ZHANG Zhiying CUI +2 位作者 Jianhan ZHANG fengwu bai Zhifeng WANG 《Frontiers in Energy》 SCIE CSCD 2019年第3期590-596,共7页
The parabolic trough solar concentrating system has been well developed and widely used in commercial solar thermal power plants. However, the conventional system has its drawbacks when connecting receiver tube parts ... The parabolic trough solar concentrating system has been well developed and widely used in commercial solar thermal power plants. However, the conventional system has its drawbacks when connecting receiver tube parts and enhancing the concentration ratio. To overcome those inherent disadvantages, in this paper, an innovative concept of linear focus secondary trough concentrating system was proposed, which consists of a fixed parabolic trough concentrator, one or more heliostats, and a fixed tube receiver. The proposed system not only avoids the end loss and connection problem on the receiver during the tracking process but also opens up the possibility to increase the concentration ratio by enlarging aperture. The design scheme of the proposed system was elaborated in detail in this paper.Besides, the optical performance of the semi and the whole secondary solar trough concentrator was evaluated by using the ray tracing method. This innovative solar concentrating system shows a high application value as a solar energy experimental device. 展开更多
关键词 SECONDARY PARABOLIC TROUGH solar CONCENTRATOR ray tracing method LINEAR FOCUS concentration ratio optical performance
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