Background:Evaluation of corneal biomechanical properties 3 months after using rigid gas permeable(RGP)contact lenses in keratoconus.Methods:In this prospective trial study,cases were 32 keratoconic eyes with no histo...Background:Evaluation of corneal biomechanical properties 3 months after using rigid gas permeable(RGP)contact lenses in keratoconus.Methods:In this prospective trial study,cases were 32 keratoconic eyes with no history of RGP lens wear.All eyes were examined with the Ocular Response Analyzer(ORA)and the Corneal Visualization Scheimpflug Technology(CORVIS-ST)to measure corneal hysteresis(CH),corneal resistance factor(CRF),deformation amplitude(DA),applanation velocity(AV)1 and 2,applanation length(AL)1 and 2,and peak distance before and 3 months after fitting aspheric RGP lenses.The effect of the correlation between contralateral eyes and maximum keratometry were controlled for in the analysis.Results were compared using repeated measures analysis of covariance.Results:At 3 months,neither the increases in mean CH(0.14±2.77 mm Hg,P=0.789),CRF(0.41±4.35 mm Hg,P=0.612),AV1(0.03±0.17 m/s,P=0.301),AV2(0.11±0.59 m/s,P=0.299),AL1(0.44±1.56 m/s,P=0.118),AL2(1.16±5.06 m/s,P=0.211),and peak distance(0.19±1.29 m/s,P=0.409),nor the decrease in mean DA(0.03±0.17 mm,P=0.402)was statistically significant.Conclusions:Results in our series of patients indicated that 3 months of RGP lens wear had no significant impact on corneal biomechanics,and perhaps non progression of keratoconus.Therefore,RGP lenses can be regarded safe and appropriate in keratoconic patients.展开更多
文摘Background:Evaluation of corneal biomechanical properties 3 months after using rigid gas permeable(RGP)contact lenses in keratoconus.Methods:In this prospective trial study,cases were 32 keratoconic eyes with no history of RGP lens wear.All eyes were examined with the Ocular Response Analyzer(ORA)and the Corneal Visualization Scheimpflug Technology(CORVIS-ST)to measure corneal hysteresis(CH),corneal resistance factor(CRF),deformation amplitude(DA),applanation velocity(AV)1 and 2,applanation length(AL)1 and 2,and peak distance before and 3 months after fitting aspheric RGP lenses.The effect of the correlation between contralateral eyes and maximum keratometry were controlled for in the analysis.Results were compared using repeated measures analysis of covariance.Results:At 3 months,neither the increases in mean CH(0.14±2.77 mm Hg,P=0.789),CRF(0.41±4.35 mm Hg,P=0.612),AV1(0.03±0.17 m/s,P=0.301),AV2(0.11±0.59 m/s,P=0.299),AL1(0.44±1.56 m/s,P=0.118),AL2(1.16±5.06 m/s,P=0.211),and peak distance(0.19±1.29 m/s,P=0.409),nor the decrease in mean DA(0.03±0.17 mm,P=0.402)was statistically significant.Conclusions:Results in our series of patients indicated that 3 months of RGP lens wear had no significant impact on corneal biomechanics,and perhaps non progression of keratoconus.Therefore,RGP lenses can be regarded safe and appropriate in keratoconic patients.