AIM:To investigate hepatitis C virus(HCV) seroprevalence in Tunisian patients with diabetes mellitus and in a control group.METHODS:A cross-sectional study was conducted to determine the HCV seroprevalence in 1269 pat...AIM:To investigate hepatitis C virus(HCV) seroprevalence in Tunisian patients with diabetes mellitus and in a control group.METHODS:A cross-sectional study was conducted to determine the HCV seroprevalence in 1269 patients with diabetes(452 male,817 female) and 1315 nondiabetic patients,attending health centers in Sousse,Tunisia.HCV screening was performed in both groups using a fourth-generation enzyme immunoassay.RESULTS:In the diabetic group,17(1.3%) were found to be HCV-infected compared with eight(0.6%) in the control group,although the difference was not significant(P=0.057).Quantitative PCR was performed in 20 patients.Eleven patients were positive and showed HCV genotype 1b in all cases.CONCLUSION:Frequency of HCV antibodies was low in patients with diabetes and in the control group in central Tunisia,with no signifi cant difference between the groups.展开更多
Granulocytic sarcoma is an uncommon and localized extramedullary tumor composed of immature granu-locytic cells.It may present in association with acute myeloid leukaemia,myelodysplastic syndrome and chronic myelogeno...Granulocytic sarcoma is an uncommon and localized extramedullary tumor composed of immature granu-locytic cells.It may present in association with acute myeloid leukaemia,myelodysplastic syndrome and chronic myelogenous leukaemia.Granulocytic sarcoma may occur in any anatomical site but involvement of the gastrointestinal tract is rare,especially in the rectum.We report on the case of a 17 year old female who presented with rectal bleeding,abdominal pain and weight loss one mo prior to admission.Recto-sigmoidoscopy revealed a rectal polypoid and ulcerated mass.The histological examination of the mass showed granulocytic sarcoma.Bone marrow examination was compatible with acute promyelocytic leukaemia(FABtype M3).This case report is a reminder of this peculiar sign of tumoral syndrome in acute myeloid leukaemia.We also discuss diagnostic methods and analyze the disease course.展开更多
文摘AIM:To investigate hepatitis C virus(HCV) seroprevalence in Tunisian patients with diabetes mellitus and in a control group.METHODS:A cross-sectional study was conducted to determine the HCV seroprevalence in 1269 patients with diabetes(452 male,817 female) and 1315 nondiabetic patients,attending health centers in Sousse,Tunisia.HCV screening was performed in both groups using a fourth-generation enzyme immunoassay.RESULTS:In the diabetic group,17(1.3%) were found to be HCV-infected compared with eight(0.6%) in the control group,although the difference was not significant(P=0.057).Quantitative PCR was performed in 20 patients.Eleven patients were positive and showed HCV genotype 1b in all cases.CONCLUSION:Frequency of HCV antibodies was low in patients with diabetes and in the control group in central Tunisia,with no signifi cant difference between the groups.
文摘Granulocytic sarcoma is an uncommon and localized extramedullary tumor composed of immature granu-locytic cells.It may present in association with acute myeloid leukaemia,myelodysplastic syndrome and chronic myelogenous leukaemia.Granulocytic sarcoma may occur in any anatomical site but involvement of the gastrointestinal tract is rare,especially in the rectum.We report on the case of a 17 year old female who presented with rectal bleeding,abdominal pain and weight loss one mo prior to admission.Recto-sigmoidoscopy revealed a rectal polypoid and ulcerated mass.The histological examination of the mass showed granulocytic sarcoma.Bone marrow examination was compatible with acute promyelocytic leukaemia(FABtype M3).This case report is a reminder of this peculiar sign of tumoral syndrome in acute myeloid leukaemia.We also discuss diagnostic methods and analyze the disease course.
