<strong>Background: </strong>Coronavirus Disease 2019 (COVID-19) has infected millions people worldwide and is continuing to spread rapidly. Patients with COVID-19 may be superinfected with other microorga...<strong>Background: </strong>Coronavirus Disease 2019 (COVID-19) has infected millions people worldwide and is continuing to spread rapidly. Patients with COVID-19 may be superinfected with other microorganisms. The prevalence of bacterial superinfection among coronavirus patients is not well understood. <strong>Aim:</strong> The aim of presenting this case is to highlight the problem of Multi-Drug Resistant (MDR) bacterial infection in COVID-19 patients. <strong>Case Presentation: </strong>Here we reported a 46 years old patient with the previous history of <em>Escherichia coli </em>urinary tract infection. A few weeks later, the patient was recovered from COVID-19 infection and was treated with antiviral therapy until PCR results become negative. Meanwhile, the patients developed urinary tract infection with MDR <em>Escherichia coli</em> even resistant to imipenem and required a critical treatment. <strong>Conclusion: </strong>Our finding suggests that greater attention should be paid to coronavirus infection complications and prophylaxis use of antibiotics. In addition, more studies are required to better understand the risk factors which are responsible for the superinfection and emergence of drug-resistant strains during COVID-19 infection.展开更多
文摘<strong>Background: </strong>Coronavirus Disease 2019 (COVID-19) has infected millions people worldwide and is continuing to spread rapidly. Patients with COVID-19 may be superinfected with other microorganisms. The prevalence of bacterial superinfection among coronavirus patients is not well understood. <strong>Aim:</strong> The aim of presenting this case is to highlight the problem of Multi-Drug Resistant (MDR) bacterial infection in COVID-19 patients. <strong>Case Presentation: </strong>Here we reported a 46 years old patient with the previous history of <em>Escherichia coli </em>urinary tract infection. A few weeks later, the patient was recovered from COVID-19 infection and was treated with antiviral therapy until PCR results become negative. Meanwhile, the patients developed urinary tract infection with MDR <em>Escherichia coli</em> even resistant to imipenem and required a critical treatment. <strong>Conclusion: </strong>Our finding suggests that greater attention should be paid to coronavirus infection complications and prophylaxis use of antibiotics. In addition, more studies are required to better understand the risk factors which are responsible for the superinfection and emergence of drug-resistant strains during COVID-19 infection.