To the Editor： Imiquimod 5% cream is currently approved for topical treatment of condyloma acuminatum. The possible side effects of vitiligo or vitiligo-like hypopigmentation associated with imiquimod treatment have ...To the Editor： Imiquimod 5% cream is currently approved for topical treatment of condyloma acuminatum. The possible side effects of vitiligo or vitiligo-like hypopigmentation associated with imiquimod treatment have rarely been reported in the open literature. We herein presented 6 cases of imiquimod-induced genital hypopigmentation.展开更多
To the Editor： Syphilis is primarily a sexually transmitted disease caused by Treponema pallidum, which can be present in various body fluids such as blood, saliva, sperm, cerebrospinal fluid, and also in active skin...To the Editor： Syphilis is primarily a sexually transmitted disease caused by Treponema pallidum, which can be present in various body fluids such as blood, saliva, sperm, cerebrospinal fluid, and also in active skin lesions,i^i Acquired syphilis contracted by Children is highly attributed to sexual abuse; however, infection can also occur by nonsexual contact： for example, prechewing feeding, kissing, fondling, or by contaminated utensils, particularly when family members or caregivers have active syphilis.展开更多
To the Editor:Syphilis is a sexually transmitted disease caused by Treponema pallidum(T.pallidum).Secondary syphilitic lesions usually occur within 3 months after the initial exposure to T.pallidum.The most frequent s...To the Editor:Syphilis is a sexually transmitted disease caused by Treponema pallidum(T.pallidum).Secondary syphilitic lesions usually occur within 3 months after the initial exposure to T.pallidum.The most frequent skin manifestations of secondary syphilis are macular and papular eruptions.However,other uncommon lesions,such as nodular,pustular,arcuate,and psoriasislike lesions,have been occasionally reported.[1,2]Annular syphilitic lesions are relatively rare and usually present as multiple lesions scattered over the body or are limited to local skin such as genital.[1,3]Herein,we report a solitary annular lesion of secondary syphilis on the face.展开更多
文摘To the Editor： Imiquimod 5% cream is currently approved for topical treatment of condyloma acuminatum. The possible side effects of vitiligo or vitiligo-like hypopigmentation associated with imiquimod treatment have rarely been reported in the open literature. We herein presented 6 cases of imiquimod-induced genital hypopigmentation.
文摘To the Editor： Syphilis is primarily a sexually transmitted disease caused by Treponema pallidum, which can be present in various body fluids such as blood, saliva, sperm, cerebrospinal fluid, and also in active skin lesions,i^i Acquired syphilis contracted by Children is highly attributed to sexual abuse; however, infection can also occur by nonsexual contact： for example, prechewing feeding, kissing, fondling, or by contaminated utensils, particularly when family members or caregivers have active syphilis.
文摘To the Editor:Syphilis is a sexually transmitted disease caused by Treponema pallidum(T.pallidum).Secondary syphilitic lesions usually occur within 3 months after the initial exposure to T.pallidum.The most frequent skin manifestations of secondary syphilis are macular and papular eruptions.However,other uncommon lesions,such as nodular,pustular,arcuate,and psoriasislike lesions,have been occasionally reported.[1,2]Annular syphilitic lesions are relatively rare and usually present as multiple lesions scattered over the body or are limited to local skin such as genital.[1,3]Herein,we report a solitary annular lesion of secondary syphilis on the face.
