Gastric cancer is one of the most common malignant tumors,for patients with advanced gastric cancer,the traditional treatment is mainly chemotherapy or combined targeted therapy;however,these have not achieved ideal e...Gastric cancer is one of the most common malignant tumors,for patients with advanced gastric cancer,the traditional treatment is mainly chemotherapy or combined targeted therapy;however,these have not achieved ideal efficacy.However,with the continuous deepening of research on molecular targeted drugs and immunosuppressants,the treatment of advanced gastric cancer patients has made new progress,and some new technologies have also been continuously emerged and applied,which brings hope for the treatment of advanced gastric cancer.Recently,several multicenter randomized controlled phase III studies on immunotherapy for advanced gastric cancer yielded encouraging results,demonstrating its superior efficacy in the treatment of advanced gastric cancer.However,prospective data to support the acceptance of surgery and the R0 removal rate following conversion therapy with immune checkpoint inhibitors are lacking.In this study,a 58-year-old woman with advanced gastric cancer and positive PD-L1 expression,negative HER-2 expression,and microsatellite stable status received immunochemotherapy combined with traditional Chinese medicine to achieve R0 resection and satisfactory efficacy.展开更多
The diagnosis of metabolic-associated fatty liver disease is based on the detection of liver steatosis together with the presence of metabolic dysfunction.According to this new definition,the diagnosis of metabolic-as...The diagnosis of metabolic-associated fatty liver disease is based on the detection of liver steatosis together with the presence of metabolic dysfunction.According to this new definition,the diagnosis of metabolic-associated fatty liver disease is independent of the amount of alcohol consumed.Actually,alcohol and its metabolites have various effects on metabolicassociated abnormalities during the process of alcohol metabolism.Studies have shown improved metabolic function in light to moderate alcohol drinkers.There are several studies focusing on the role of light to moderate alcohol intake on metabolic dysfunction.However,the results from studies are diverse,and the conclusions are often controversial.This review systematically discusses the effects of alcohol consumption,focusing on light to moderate alcohol consumption,obesity,lipid and glucose metabolism,and blood pressure.展开更多
文摘Gastric cancer is one of the most common malignant tumors,for patients with advanced gastric cancer,the traditional treatment is mainly chemotherapy or combined targeted therapy;however,these have not achieved ideal efficacy.However,with the continuous deepening of research on molecular targeted drugs and immunosuppressants,the treatment of advanced gastric cancer patients has made new progress,and some new technologies have also been continuously emerged and applied,which brings hope for the treatment of advanced gastric cancer.Recently,several multicenter randomized controlled phase III studies on immunotherapy for advanced gastric cancer yielded encouraging results,demonstrating its superior efficacy in the treatment of advanced gastric cancer.However,prospective data to support the acceptance of surgery and the R0 removal rate following conversion therapy with immune checkpoint inhibitors are lacking.In this study,a 58-year-old woman with advanced gastric cancer and positive PD-L1 expression,negative HER-2 expression,and microsatellite stable status received immunochemotherapy combined with traditional Chinese medicine to achieve R0 resection and satisfactory efficacy.
文摘The diagnosis of metabolic-associated fatty liver disease is based on the detection of liver steatosis together with the presence of metabolic dysfunction.According to this new definition,the diagnosis of metabolic-associated fatty liver disease is independent of the amount of alcohol consumed.Actually,alcohol and its metabolites have various effects on metabolicassociated abnormalities during the process of alcohol metabolism.Studies have shown improved metabolic function in light to moderate alcohol drinkers.There are several studies focusing on the role of light to moderate alcohol intake on metabolic dysfunction.However,the results from studies are diverse,and the conclusions are often controversial.This review systematically discusses the effects of alcohol consumption,focusing on light to moderate alcohol consumption,obesity,lipid and glucose metabolism,and blood pressure.
