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PKM2 controls the degranulation of secondary and tertiary granules in neutrophils by phosphorylating SNAP-23
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作者 Xinlei Sun Dong Wang +5 位作者 Yan Wang Lei Ye fujie shi Shuang Qu Hongwei Liang Ke Zen 《Cellular & Molecular Immunology》 SCIE CAS CSCD 2021年第8期2048-2050,共3页
Polymorphonuclear neutrophils(PMNs)possess multiple distinct types of cytoplasmic granules:secondary granules,tertiary granules,and azurophil granules[1].It has been suggested that PMN degranulation is controlled by e... Polymorphonuclear neutrophils(PMNs)possess multiple distinct types of cytoplasmic granules:secondary granules,tertiary granules,and azurophil granules[1].It has been suggested that PMN degranulation is controlled by exocytotic machinery comprising membrane-specific SNARE proteins,soluble N-ethylmaleimide sensitive factor(NSF)and soluble NSF-attaching proteins[2]. 展开更多
关键词 PKM2 NEUTROPHILS TERTIARY
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