Background: The colonic pit pattern is recognized as an aid to the differential diagnosis between hyperplastic lesions, adenoma, and carcinoma, and is a focus for observation by magnification chromoendoscopy, especial...Background: The colonic pit pattern is recognized as an aid to the differential diagnosis between hyperplastic lesions, adenoma, and carcinoma, and is a focus for observation by magnification chromoendoscopy, especially in Japan. This study evaluated intra-and interobserver agreement of experienced endoscopists in the assessment of colonic pit patterns when using the Kudo classification. Methods: A total of 220 magnification chromoendoscopic pictures of colonic lesions were selected, of which 215 were collected from a consecutive series of patients. The pictures were randomly displayed twice to 6 experienced endoscopists at an interval of 1 week. Each picture was assessed for predominant pit pattern by using the classification of Kudo. Histopathologic diagnosis also was predicted based on the pit pattern diagnosis. Kappa statistics were used to estimate intra-and interobserver variation. Results: The mean (standard deviation) inter-and intra-observer kappa values for experienced endoscopists were 0.716 (0.031) and 0.810 (0.084), respectively. For prediction of histopathology according to the pit pattern diagnosis, the mean (standard deviation) inter-and intra-observer kappa values were 0.776 (0.032) (p = 0.001)and 0.862 (0.069) (p = 0.028), respectively. Conclusions: For experienced endoscopists, the inter-and intra-observer reproducibility of the classification of colonic pit pattern is good.展开更多
Recent reports on the results of endoscopic ablation of Barrett’s mucosa have been promising, particularly when total mucosal ablation is coupled with aggres sive acid-suppression treatment using high-dose proton-pum...Recent reports on the results of endoscopic ablation of Barrett’s mucosa have been promising, particularly when total mucosal ablation is coupled with aggres sive acid-suppression treatment using high-dose proton-pump inhibitor therapy . There is also a considerable literature on reepithelialization after ablative treatments in Barrett’s esophagus. This report describes a case of multifocal s uperficial adenocarcinoma arising in Barrett’s mucosa that was successfully tre ated with total circumferential endoscopic mucosal resection, with a subsequent follow-up of more than 2 years. This is the first report describing the process of squamous reepithelialization after endoscopic mucosal resection in Barrett’ s esophagus.展开更多
文摘Background: The colonic pit pattern is recognized as an aid to the differential diagnosis between hyperplastic lesions, adenoma, and carcinoma, and is a focus for observation by magnification chromoendoscopy, especially in Japan. This study evaluated intra-and interobserver agreement of experienced endoscopists in the assessment of colonic pit patterns when using the Kudo classification. Methods: A total of 220 magnification chromoendoscopic pictures of colonic lesions were selected, of which 215 were collected from a consecutive series of patients. The pictures were randomly displayed twice to 6 experienced endoscopists at an interval of 1 week. Each picture was assessed for predominant pit pattern by using the classification of Kudo. Histopathologic diagnosis also was predicted based on the pit pattern diagnosis. Kappa statistics were used to estimate intra-and interobserver variation. Results: The mean (standard deviation) inter-and intra-observer kappa values for experienced endoscopists were 0.716 (0.031) and 0.810 (0.084), respectively. For prediction of histopathology according to the pit pattern diagnosis, the mean (standard deviation) inter-and intra-observer kappa values were 0.776 (0.032) (p = 0.001)and 0.862 (0.069) (p = 0.028), respectively. Conclusions: For experienced endoscopists, the inter-and intra-observer reproducibility of the classification of colonic pit pattern is good.
文摘Recent reports on the results of endoscopic ablation of Barrett’s mucosa have been promising, particularly when total mucosal ablation is coupled with aggres sive acid-suppression treatment using high-dose proton-pump inhibitor therapy . There is also a considerable literature on reepithelialization after ablative treatments in Barrett’s esophagus. This report describes a case of multifocal s uperficial adenocarcinoma arising in Barrett’s mucosa that was successfully tre ated with total circumferential endoscopic mucosal resection, with a subsequent follow-up of more than 2 years. This is the first report describing the process of squamous reepithelialization after endoscopic mucosal resection in Barrett’ s esophagus.
