HER2 gene status and the relationship with p21 protein expression in gastric cancer

我们瞄准了到分析的目的有在胃的癌的 p21 蛋白质表示的 HER2 基因地位和它的关系。在 situ 杂交(鱼) 和 immunohistochemistry (IHC ) 的方法荧光技术被用来在胃的癌症的 59 种情况中检测 HER2 基因地位和 p53 蛋白质。HER2 基因扩大率的结果鱼察觉是 16.9%(10/59 ) ，在没有拷贝数字获得的 49 种情况中的 HER2 基因扩大和基因扩大是 49.2% 的一个总数(29/59 ) 。HER2 蛋白质表示是 42.4%(25/59 ) ，在有 +++ 的病人的 HER2 基因扩大率，， ++ HER2 蛋白质表示在有 + HER2 蛋白质表示的病人是 3/3 和 5/8，它是 2/14，有重要差别(P < 0.05 ) 。p21 蛋白质表示率是 49.2%(29/59 ) ， HER2 基因扩大率和 p21 蛋白质表示在肿瘤侵略深度有重要差别，淋巴节点转移(P < 0.05 ) ；在组织学的类型的有的不统计的意义，变老，性差别(P > 0.05 ) 。结论 HER2 基因扩大率和基因拷贝数字断然与 p21 蛋白质表示， HER2 基因地位和联合察觉能提供的 p21 蛋白质的表示有关联在胃的癌症转移，病人条件开发和预后的引用值，它能也指导单个治疗的临床的开发。

Impact of Doctoral Student Training Process Fit on Doctoral Students’ Mental Health

Background:Doctoral students have much higher risk of anxiety or depression than general population.Doctoral students worldwide are facing varying degrees of mental health risks.Method:Based on the survey data of 6,812 doctoral students worldwide in Nature in 2019,Probit and Logit models are used to explore the correlation between thefit of doctoral education and training process and the mental health of doctoral students.Results:(1)The training environmentfit of doctoral students has a significant positive impact on their mental health.(2)The academic professionfit of doctoral students has a significant positive impact on their mental health.(3)The orga-nizational culturefit of doctoral students has a significant positive impact on their mental health.(4)Thefinancial supportfit of doctoral students has a significant positive impact on their mental health.Conclusion:The higher the degree of doctoral students’training environmentfit,academic professionfit,organizational culturefit,andfinancial supportfit,the lower the possibility of anxiety or depression among doctoral students.The current research results can help reveal extensive factors that affect the mental health of doctoral students,facilitate the planning and development of effective intervention measures by universities,improve thefit of the doctoral education and training process,improve the mental health of doctoral students,and boost academic excellence.

Study on Dynamic Model of Initial Emission Rights for Medical Sewage System

The chemical oxygen demand (COD) is selected as the index in this paper. The system dynamics method is used to analyze the emission right price of medical sewage, the boundary of the emission right price system is determined, and the system dynamics model of the initial emission right of medical sewage is constructed, in which the system is divided into water resources subsystem, population subsystem, economic subsystem and social subsystem. It is expected to expand the theory of the system modeling of the initial discharge right of medical sewage, and to provide the basis for the relevant decision of the environmental management authorities.