Correlation study of relative parameters of intracranial pressure and prognosis of patient with craniocerebral injury

Objective:To analyze the correlation of the relative parameters of intracranial pressure to the prognosis in patients with craniocerebral injury.Methods:The clinical data of 80 patients with closed craniocerebral injury were retrospectively analyzed,and all of these patients underwent conventional examinations of arterial blood pressure and intracranial pressure.Neumatic DCR system was used to monitor relative parameters of intracranial pressure from patients.According to the score of Glasgow outcome scale(GOS)upon discharge,they were divided into favorable prognosis group(GOSⅢ-Ⅴ,n=46)and unfavorable prognosis group(GOSⅠ-Ⅱ,n=34).The relative parameters of intracranial pressure of two groups were compared so as to analyze the correlation of the prognosis in patients to ICP-related parameters.Results:Pressure reactivity index(PRx)and intracranial pressure(ICP)of favorable prognosis group were significantly higher than those of unfavorable prognosis group(t=12.27,t=5.22,p<0.05).Meanwhile,cerebral perfusion pressure(CPP)and ICP-ABP wave amplitude correlation(IAAC)of favorable prognosis group were significantly lower than those of unfavorable prognosis group(t=14.54,t=14.78,p<0.05).The average age,gender,duration of admission to neurosurgical intensive care unit(NICU)and GCS(Glasgow coma scale)score on admission of the two groups were not statistically significant.Conclusions:The prognosis and ICP-related parameters(such as PRx,ICP,CPP,etc.)in patients with craniocerebral injury are risk factors for the prognosis effect.Therefore,to monitor the above-mentioned indicators has an important clinical value for assessing the prognosis of craniocerebral injury.

Clinical characteristics of hepatopulmonary syndrome and hepatorenal syndrome and associated therapeutic potential of transjugular intrahepatic portosystemic shunt

Hepatorenal syndrome(HRS)and hepatopulmonary syndrome(HPS)are two serious complications of liver disease,causing damage not only to the liver but also to the kidneys,lungs,and heart.HRS and HPS affect the patient's circulatory and respiratory systems,with poor prognosis and high mortality in clinical practice.There is a lack of effective treatment other than liver transplantation.Transjugular intrahepatic portosystemic shunt(TIPS)is an effective tool to prolong the survival of patients with advanced liver disease and is mainly used to treat portal hypertension and ascites because it can effectively reduce portal pressure.Studies on the treatment of both of these complications with TIPS are limited and deserve further study because the therapeutic effects of TIPS have the potential to improve the prognosis of severe liver disease.This article reviews the clinical features of HRS and HPS,the consequences of these syndromes,and the potential mechanistic effects after TIPS intervention.

Problems in treatment and training of autistic children growing up in China:A follow‐up case report

Introduction Currently,interventions for children with autism spectrum disorders(ASD)in China are mainly carried out by professionals in rehabilitation institutions and special schools.However,when autistic children are older,they do not receive effective training and treatment,and there is no specific place in society to accommodate autistic adults.Mental hospitals are usually their ultimate home.Case presentation We report a 22‐year‐old male with ASD.The manifestation and/or intervention from the age of 3 years to now were recorded.He has been hospitalized in the closed ward of a mental hospital since 2015.Conclusion This report typically present the current problems in treatment and training of autistic children growing up in China.Life‐long rehabilitation training is important for every patient with ASD.Relevant policies and resources in China should be optimized in terms of medical treatment and health care,education and training,social assistance,social security,labor employment,and social culture.