Lipid lowering is the cornerstone in the prevention of cardiovascular disease(CVD),which is based on a plethora of data bolstering the causal role of low-density lipoprotein cholesterol(LDL-C)in the process of atheros...Lipid lowering is the cornerstone in the prevention of cardiovascular disease(CVD),which is based on a plethora of data bolstering the causal role of low-density lipoprotein cholesterol(LDL-C)in the process of atherosclerosis.However,a concern that has been raised in this regard is whether LDL-C lowering agents,or the subsequent low LDL-C levels,result in cognitive impairment,offsetting the beneficial effect of LDL-C lowering on CVD outcomes.展开更多
文摘Lipid lowering is the cornerstone in the prevention of cardiovascular disease(CVD),which is based on a plethora of data bolstering the causal role of low-density lipoprotein cholesterol(LDL-C)in the process of atherosclerosis.However,a concern that has been raised in this regard is whether LDL-C lowering agents,or the subsequent low LDL-C levels,result in cognitive impairment,offsetting the beneficial effect of LDL-C lowering on CVD outcomes.