Objective: To assess the efficacy of a new application technique of mitomycin to enhance the outcome of filtering surgery in cases of uncontrolled glaucoma in eyes without previous filtering surgery. Methods: We perfo...Objective: To assess the efficacy of a new application technique of mitomycin to enhance the outcome of filtering surgery in cases of uncontrolled glaucoma in eyes without previous filtering surgery. Methods: We performed a prospective, randomized clinical trial. Forty-two consecutive patients scheduled for glaucoma surgery in one large surgical center were included on a consecutive basis. Patients underwent routine trabeculectomy.展开更多
Purpose: Metalloproteinases (MMP) and their inhibitors (TIMP) are essential for assembly and remodelling of fibrous tissue all over the body. We aimed to detect different MMPs and TIMPs in Tenon fibroblasts to determi...Purpose: Metalloproteinases (MMP) and their inhibitors (TIMP) are essential for assembly and remodelling of fibrous tissue all over the body. We aimed to detect different MMPs and TIMPs in Tenon fibroblasts to determine the presence of this mechanism in the human conjunctiva If it is possible to use the MMP and TIMP system to prevent permanent tissue alterations, this would possibly have an impact on future filtering surgery.展开更多
文摘Objective: To assess the efficacy of a new application technique of mitomycin to enhance the outcome of filtering surgery in cases of uncontrolled glaucoma in eyes without previous filtering surgery. Methods: We performed a prospective, randomized clinical trial. Forty-two consecutive patients scheduled for glaucoma surgery in one large surgical center were included on a consecutive basis. Patients underwent routine trabeculectomy.
文摘Purpose: Metalloproteinases (MMP) and their inhibitors (TIMP) are essential for assembly and remodelling of fibrous tissue all over the body. We aimed to detect different MMPs and TIMPs in Tenon fibroblasts to determine the presence of this mechanism in the human conjunctiva If it is possible to use the MMP and TIMP system to prevent permanent tissue alterations, this would possibly have an impact on future filtering surgery.
