With moorings equipped with Acoustic Doppler Current Profilers （ADCP） in the northern South China Sea （SCS） in 2008 and 2009, we observed three near-inertial oscillation （NIO） events coded 2008a, 2009a and 2009b...With moorings equipped with Acoustic Doppler Current Profilers （ADCP） in the northern South China Sea （SCS） in 2008 and 2009, we observed three near-inertial oscillation （NIO） events coded 2008a, 2009a and 2009b induced by passages of typhoons or tropical storms. This study compares characteristics of the three NIO events. Event 2008a was the strongest one among the three, and had the longest sustaining period （15 d）, while events 2009a and 2009b sustained for only 4 and 8 d, respectively. The three events were distinguished by vertical energy distribution and phase propagation. As for the frequency shift of the NIO, event 2008a had a peak frequency lower than the local Coriolis frequency （red-shift）, while events 2009a and 2009b showed blue-shift. The behavior of individual NIO event is jointly decided by the typhoon disturbance and the background ocean condition. Especially the background flow plays an important role by effects of advection and modulation. The results in this study provide observational evidence of variational NIO response to background flow field. As indicated by the distribution of vorticity and effective Coriolis frequency derived from numerical modeling, the large amplitude and elongated sustaining period of event 2008a were attributed to the waveguide effect of the background shear flow. This effect redistributed the NIO energy after the typhoon passage, absorbed incident waves and trapped energy in the area of the negative vorticity. While the background flow during events 2009a and 2009b did not have such effects due to the near-zero vorticity in the mooring area.展开更多
OBJECTIVE:To evaluate the clinical efficacy and safety of Rebixiao(RBX)Chinese herbal tablets(CHT)and Chinese formula granules(CFG)in the treatment of acute gout arthritis(AGA).METHODS:This randomized,multicenter,doub...OBJECTIVE:To evaluate the clinical efficacy and safety of Rebixiao(RBX)Chinese herbal tablets(CHT)and Chinese formula granules(CFG)in the treatment of acute gout arthritis(AGA).METHODS:This randomized,multicenter,double-blind,controlled trial included 165 AGA patients with the damp-heat symptom pattern who were randomly divided into an RBX CHT group and an RBX CFG group and treated for 7 d at three centers.The total effective rates of the joint symptom score,Traditional Chinese Medicine(TCM)symptoms score,erythrocyte sedimentation rate(ESR),and C-reactive protein(CRP)were used to evaluate the clinical efficacy.Safety assessments were also performed.RESULTS:Of the 165 enrolled patients,147 completed the clinical observation.There was no difference in baseline between the two groups.The total effective rates of the joint symptom score were 94.36%and 97.36%,and the total effective rates of the TCM symptoms score were 95.77%and 97.36%in the CFG group and CHT group,respectively.No statistical difference was found between the two groups(P>0.05).Additionally,ESR and CRP were similar in both groups(P>0.05).Furthermore,treatment efficacy regarding TCM and joint symptoms,the ESR,and CRP were consistent within each center and among the different centers(P>0.05).In addition,the incidence of adverse events was 4.22%and 2.63%in the CFG group and CHT group,respectively,and no difference was observed between the two groups(P>0.05).CONCLUSION:RBX CFG and CHT have significant and similar efficacy in the treatment of AGA,and CFG did not increase adverse side effects.展开更多
基金The National Basic Research Program(973 Program) of China under contract Nos 2015CB954004 and 2009CB421208the National Natural Science Foundation of China under contract Nos 41276006U1405233 and 40976013the Open Fund of the Key Laboratory of Ocean Circulation and Waves,Chinese Academy of Sciences under contract No.KLOCAW1307
文摘With moorings equipped with Acoustic Doppler Current Profilers （ADCP） in the northern South China Sea （SCS） in 2008 and 2009, we observed three near-inertial oscillation （NIO） events coded 2008a, 2009a and 2009b induced by passages of typhoons or tropical storms. This study compares characteristics of the three NIO events. Event 2008a was the strongest one among the three, and had the longest sustaining period （15 d）, while events 2009a and 2009b sustained for only 4 and 8 d, respectively. The three events were distinguished by vertical energy distribution and phase propagation. As for the frequency shift of the NIO, event 2008a had a peak frequency lower than the local Coriolis frequency （red-shift）, while events 2009a and 2009b showed blue-shift. The behavior of individual NIO event is jointly decided by the typhoon disturbance and the background ocean condition. Especially the background flow plays an important role by effects of advection and modulation. The results in this study provide observational evidence of variational NIO response to background flow field. As indicated by the distribution of vorticity and effective Coriolis frequency derived from numerical modeling, the large amplitude and elongated sustaining period of event 2008a were attributed to the waveguide effect of the background shear flow. This effect redistributed the NIO energy after the typhoon passage, absorbed incident waves and trapped energy in the area of the negative vorticity. While the background flow during events 2009a and 2009b did not have such effects due to the near-zero vorticity in the mooring area.
基金grants from the Traditional Chinese Medicine Department of Chongqing Municipal Health and Family Planning commission(No.2012-1-16)National Natural Science Foundation of China(Grant no.81673724)+1 种基金Chongqing Science and Technology Commission(cstc2018jxj1130084 and cstc2017jxjl130033)Chongqing Hospital of Traditional Chinese Medicine Advantageous Diseases Special Fund(No.cqszyyysbz2018004)。
文摘OBJECTIVE:To evaluate the clinical efficacy and safety of Rebixiao(RBX)Chinese herbal tablets(CHT)and Chinese formula granules(CFG)in the treatment of acute gout arthritis(AGA).METHODS:This randomized,multicenter,double-blind,controlled trial included 165 AGA patients with the damp-heat symptom pattern who were randomly divided into an RBX CHT group and an RBX CFG group and treated for 7 d at three centers.The total effective rates of the joint symptom score,Traditional Chinese Medicine(TCM)symptoms score,erythrocyte sedimentation rate(ESR),and C-reactive protein(CRP)were used to evaluate the clinical efficacy.Safety assessments were also performed.RESULTS:Of the 165 enrolled patients,147 completed the clinical observation.There was no difference in baseline between the two groups.The total effective rates of the joint symptom score were 94.36%and 97.36%,and the total effective rates of the TCM symptoms score were 95.77%and 97.36%in the CFG group and CHT group,respectively.No statistical difference was found between the two groups(P>0.05).Additionally,ESR and CRP were similar in both groups(P>0.05).Furthermore,treatment efficacy regarding TCM and joint symptoms,the ESR,and CRP were consistent within each center and among the different centers(P>0.05).In addition,the incidence of adverse events was 4.22%and 2.63%in the CFG group and CHT group,respectively,and no difference was observed between the two groups(P>0.05).CONCLUSION:RBX CFG and CHT have significant and similar efficacy in the treatment of AGA,and CFG did not increase adverse side effects.
