目的系统评价中医药预防骨科术后下肢深静脉血栓(DVT)的临床疗效。方法计算机检索中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据资源库、PubMed、Web of science及Cochrane Library中2010年-2018年采用中医药预防骨科术后下...目的系统评价中医药预防骨科术后下肢深静脉血栓(DVT)的临床疗效。方法计算机检索中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据资源库、PubMed、Web of science及Cochrane Library中2010年-2018年采用中医药预防骨科术后下肢深静脉血栓形成的临床随机对照试验(RCT),按Cochrane偏倚风险评价系统对纳入文献进行评价,采用RevMan 5.3对结果行Meta分析。结果共纳入文献6篇,500例患者。Meta分析结果显示:中医药试验组下肢深静脉血栓发生率低于对照组[RR=0.29,95%CI(0.13,0.65)];术后D-二聚体比较试验组低于对照组[MD=-0.42,95%CI(-0.82,-0.02)];凝血酶原时间中医药试验组优于对照组[MD=1.10,95%CI(0.24,1.96)],两组比较差异有统计学意义。结论中医药在骨科术后的应用可有效预防下肢深静脉血栓的形成,拮抗术后血液高凝状态,具有较高临床价值。展开更多
Estimating the spatial distribution of coseismic slip is an ill-posed inverse problem, and solutions may be extremely oscillatory due to measurement errors without any constraints on the coseismic slip distribution. I...Estimating the spatial distribution of coseismic slip is an ill-posed inverse problem, and solutions may be extremely oscillatory due to measurement errors without any constraints on the coseismic slip distribution. In order to obtain stable solution for coseismic slip inversion, regularization method with smoothness-constrained was imposed. Trade-off parameter in regularized inversion, which balances the minimization of the data misfit and model roughness, should be a critical procedure to achieve both resolution and stability. Then, the active constraint balancing approach is adopted, in which the trade-off parameter is regarded as a spatial variable at each model parameter and automatically determined via the model resolution matrix and the spread function. Numerical experiments for a synthetical model indicate that regularized inversion using active constraint balancing approach can provides stable inversion results and have low sensitivity to the knowledge of the exact character of the Gaussian noise. Regularized inversion combined with active constraint balancing approach is conducted on the 2005 Nias earthquake. The released moment based on the estimated coseismic slip distribution is 9.91×1021 N·m, which is equivalent to a moment magnitude of 8.6 and almost identical to the value determined by USGS. The inversion results for synthetic coseismic uniform-slip model and the 2005 earthquake show that smoothness-constrained regularized inversion method combined with active constraint balancing approach is effective, and can be reasonable to reconstruct coseismic slip distribution on fault.展开更多
文摘目的系统评价中医药预防骨科术后下肢深静脉血栓(DVT)的临床疗效。方法计算机检索中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据资源库、PubMed、Web of science及Cochrane Library中2010年-2018年采用中医药预防骨科术后下肢深静脉血栓形成的临床随机对照试验(RCT),按Cochrane偏倚风险评价系统对纳入文献进行评价,采用RevMan 5.3对结果行Meta分析。结果共纳入文献6篇,500例患者。Meta分析结果显示:中医药试验组下肢深静脉血栓发生率低于对照组[RR=0.29,95%CI(0.13,0.65)];术后D-二聚体比较试验组低于对照组[MD=-0.42,95%CI(-0.82,-0.02)];凝血酶原时间中医药试验组优于对照组[MD=1.10,95%CI(0.24,1.96)],两组比较差异有统计学意义。结论中医药在骨科术后的应用可有效预防下肢深静脉血栓的形成,拮抗术后血液高凝状态,具有较高临床价值。
基金Projects(41604111,41541036) supported by the National Natural Science Foundation of China
文摘Estimating the spatial distribution of coseismic slip is an ill-posed inverse problem, and solutions may be extremely oscillatory due to measurement errors without any constraints on the coseismic slip distribution. In order to obtain stable solution for coseismic slip inversion, regularization method with smoothness-constrained was imposed. Trade-off parameter in regularized inversion, which balances the minimization of the data misfit and model roughness, should be a critical procedure to achieve both resolution and stability. Then, the active constraint balancing approach is adopted, in which the trade-off parameter is regarded as a spatial variable at each model parameter and automatically determined via the model resolution matrix and the spread function. Numerical experiments for a synthetical model indicate that regularized inversion using active constraint balancing approach can provides stable inversion results and have low sensitivity to the knowledge of the exact character of the Gaussian noise. Regularized inversion combined with active constraint balancing approach is conducted on the 2005 Nias earthquake. The released moment based on the estimated coseismic slip distribution is 9.91×1021 N·m, which is equivalent to a moment magnitude of 8.6 and almost identical to the value determined by USGS. The inversion results for synthetic coseismic uniform-slip model and the 2005 earthquake show that smoothness-constrained regularized inversion method combined with active constraint balancing approach is effective, and can be reasonable to reconstruct coseismic slip distribution on fault.
