Rheumatoid arthritis(RA)is a worldwide public health problem.Interventions to delay or prevent the onset of RA have attracted much attention in recent years,and researchers are now exploring various prevention strateg...Rheumatoid arthritis(RA)is a worldwide public health problem.Interventions to delay or prevent the onset of RA have attracted much attention in recent years,and researchers are now exploring various prevention strategies.At present,there is still no unified consensus for RA prevention,but targeting therapeutic windows and implementing interventions for at-risk individuals are extremely important.Due to the limited number of clinical trials on pharmacologic interventions,further studies are needed to explore and establish optimal intervention regimens and effective measures to prevent progression to RA.In this review,we introduce the RA disease process and risk factors,and present research on the use of both Western and Chinese medicine from clinical perspectives regarding RA prevention.Furthermore,we describe several complete and ongoing clinical studies on the use of Chinese herbal formulae for the prevention of RA.展开更多
基金Supported by the National Natural Science Foundation of China(No.82274421)the Research Project of Guangdong Provincial Hospital of Chinese Medicine(Nos.2023KT14118,YN2023RD01,YN2021RD01,MY2022KF08)+3 种基金the Specific Fund of State Key Laboratory of Dampness Syndrome of Chinese Medicine(Nos.SZ2021ZZ0202,SZ2021ZZ35)the Guangdong Provincial Key Laboratory of Chinese Medicine for Prevention and Treatment of Refractory Chronic Diseases(2018):2018B030322012(No.YN2023MB15)the Science and Technology Planning Project of Guangdong Province(Nos.2023B1212060063,YN2023ZH22)the Project of Administration of Traditional Chinese Medicine of Guangdong Province of China(No.20231112)。
文摘Rheumatoid arthritis(RA)is a worldwide public health problem.Interventions to delay or prevent the onset of RA have attracted much attention in recent years,and researchers are now exploring various prevention strategies.At present,there is still no unified consensus for RA prevention,but targeting therapeutic windows and implementing interventions for at-risk individuals are extremely important.Due to the limited number of clinical trials on pharmacologic interventions,further studies are needed to explore and establish optimal intervention regimens and effective measures to prevent progression to RA.In this review,we introduce the RA disease process and risk factors,and present research on the use of both Western and Chinese medicine from clinical perspectives regarding RA prevention.Furthermore,we describe several complete and ongoing clinical studies on the use of Chinese herbal formulae for the prevention of RA.