The synthesis of α-calcium sulfate hemihydrate (α-CSH) from flue gas desulfurization (FGD)gypsum is a good way to realize the comprehensive utilization of FGD gypsum. To obtainα-CSH with the satisfactory performanc...The synthesis of α-calcium sulfate hemihydrate (α-CSH) from flue gas desulfurization (FGD)gypsum is a good way to realize the comprehensive utilization of FGD gypsum. To obtainα-CSH with the satisfactory performances, a facile hydrothermal-aging pretreatment process for FGD gypsum raw materials was proposed, where FGD gypsum was firstly hydrothermally converted to α-CSH whiskers, and α-CSH whiskers were further hydrated to synthesize CaSO4·2H2O (CSD) by aging under the regulation of N,N'-methylenebisacrylamide (MBA). The effects of aging time, MBA addition, aging temperature, and pH on the morphology of the synthesized CSD were investigated. The synthesized CSD crystals exhibit highly uniform prismatic morphology with the length of ca 100μm and the whiteness of 91.56%. The regulation mechanism of MBA was also illustrated. The synthesized CSD crystals with prismatic morphology were further used as raw materials to synthesize the short columnar α-CSH. The absolute dry compressive strength of paste prepared from the short columnar α-CSH is 40.85 MPa, which reaches α40 strength grade.展开更多
目的探究孕妇孕期血清样本中血清十八碳一不饱和脂肪酸硬脂酰鞘氨醇(serum stearoyl sphingosine,C18∶1-Cer)和1-硬脂酰基-sn-甘油-3-磷酸胆碱(lysophosphatidyl choline,LPC18∶0)水平在预测孕妇患妊娠期糖尿病(gestational diabetes ...目的探究孕妇孕期血清样本中血清十八碳一不饱和脂肪酸硬脂酰鞘氨醇(serum stearoyl sphingosine,C18∶1-Cer)和1-硬脂酰基-sn-甘油-3-磷酸胆碱(lysophosphatidyl choline,LPC18∶0)水平在预测孕妇患妊娠期糖尿病(gestational diabetes mellitus,GDM)方面的价值。方法回顾性分析126例孕妇的临床资料和实验室指标,根据GDM诊断结果,将研究对象分为GDM组(n=66)和对照组(n=60)。采用质谱法检测研究对象孕早期和孕中期血清C18∶1-Cer和LPC18∶0水平,通过Logistic回归分析筛选出GDM的危险因素,采用受试者工作特征(receiver operating characteristic,ROC)曲线评估C18∶1-Cer,LPC188∶0和两者联合对GDM的预测价值。结果与对照组相比,GDM组血清C18∶1-Cer和LPC18∶0水平在孕早期(18.92±2.77ng/ml vs 23.47±4.18ng/ml,41.32±17.55ng/ml vs 88.08±16.02ng/ml)和孕中期(23.14±4.10ng/ml vs 18.76±4.05ng/ml,84.60±14.53ng/ml vs 40.50±17.79ng/ml)均显著升高,差异具有统计学意义(t=7.127,15.637;-5.984,2.174,均P<0.05)。C18∶1-Cer与空腹血糖(fasting plasma glucose,FPG)、空腹胰岛素(fasting plasma insulin,FPI)、胰岛素抵抗指数(homeostasis model assessment of insulin resistance,HOMA-IR)、糖化血红蛋白(glycated hemoglobin,HbA1c)和三酰甘油(triglyceride,TG)呈正相关(r=0.458,0.209,0.317,0.223,0.219,均P<0.05)。LPC18∶0与FPG,FPI,HOMA-IR,HbA1c,总胆固醇(total cholesterol,TC)和TG呈正相关(r=0.715,0.426,0.580,0.465,0.232,0.372,均P<0.05)。Logistic回归分析结果显示,C18∶1-Cer[OR(95%CI):1.522(1.136~.039),P<0.05]和LPC18∶0[OR(95%CI):1.198(1.102~1.302),P<0.001]是GDM的独立危险因素。ROC曲线分析结果显示,血清C18∶1-Cer,LPC18∶0和两指标联合的曲线下面积(area under the curve,AUC)分别为0.819,0.971和0.986,两者联合检测的预测效能优于单独检测。结论妊娠早期血清中的C18∶1-Cer和LPC18∶0与GDM的发生密切相关,C18∶1-Cer联合LPC18∶0对GDM早期诊断有一定的预测价值。展开更多
基金Funded by National Natural Science Foundation of China(No.22008049)Natural Science Foundation of Hebei Province,China (Nos.B2020202081 and B2018202330)+1 种基金Key Laboratory of Gas Hydrate,Guangzhou Institute of Energy Conversion,Chinese Academy of Sciences,China (No.E029kf1601)Research Fund Program of Science and Technology of Colleges and Universities of Hebei Province,China (No.QN2019012)。
文摘The synthesis of α-calcium sulfate hemihydrate (α-CSH) from flue gas desulfurization (FGD)gypsum is a good way to realize the comprehensive utilization of FGD gypsum. To obtainα-CSH with the satisfactory performances, a facile hydrothermal-aging pretreatment process for FGD gypsum raw materials was proposed, where FGD gypsum was firstly hydrothermally converted to α-CSH whiskers, and α-CSH whiskers were further hydrated to synthesize CaSO4·2H2O (CSD) by aging under the regulation of N,N'-methylenebisacrylamide (MBA). The effects of aging time, MBA addition, aging temperature, and pH on the morphology of the synthesized CSD were investigated. The synthesized CSD crystals exhibit highly uniform prismatic morphology with the length of ca 100μm and the whiteness of 91.56%. The regulation mechanism of MBA was also illustrated. The synthesized CSD crystals with prismatic morphology were further used as raw materials to synthesize the short columnar α-CSH. The absolute dry compressive strength of paste prepared from the short columnar α-CSH is 40.85 MPa, which reaches α40 strength grade.
文摘目的探究孕妇孕期血清样本中血清十八碳一不饱和脂肪酸硬脂酰鞘氨醇(serum stearoyl sphingosine,C18∶1-Cer)和1-硬脂酰基-sn-甘油-3-磷酸胆碱(lysophosphatidyl choline,LPC18∶0)水平在预测孕妇患妊娠期糖尿病(gestational diabetes mellitus,GDM)方面的价值。方法回顾性分析126例孕妇的临床资料和实验室指标,根据GDM诊断结果,将研究对象分为GDM组(n=66)和对照组(n=60)。采用质谱法检测研究对象孕早期和孕中期血清C18∶1-Cer和LPC18∶0水平,通过Logistic回归分析筛选出GDM的危险因素,采用受试者工作特征(receiver operating characteristic,ROC)曲线评估C18∶1-Cer,LPC188∶0和两者联合对GDM的预测价值。结果与对照组相比,GDM组血清C18∶1-Cer和LPC18∶0水平在孕早期(18.92±2.77ng/ml vs 23.47±4.18ng/ml,41.32±17.55ng/ml vs 88.08±16.02ng/ml)和孕中期(23.14±4.10ng/ml vs 18.76±4.05ng/ml,84.60±14.53ng/ml vs 40.50±17.79ng/ml)均显著升高,差异具有统计学意义(t=7.127,15.637;-5.984,2.174,均P<0.05)。C18∶1-Cer与空腹血糖(fasting plasma glucose,FPG)、空腹胰岛素(fasting plasma insulin,FPI)、胰岛素抵抗指数(homeostasis model assessment of insulin resistance,HOMA-IR)、糖化血红蛋白(glycated hemoglobin,HbA1c)和三酰甘油(triglyceride,TG)呈正相关(r=0.458,0.209,0.317,0.223,0.219,均P<0.05)。LPC18∶0与FPG,FPI,HOMA-IR,HbA1c,总胆固醇(total cholesterol,TC)和TG呈正相关(r=0.715,0.426,0.580,0.465,0.232,0.372,均P<0.05)。Logistic回归分析结果显示,C18∶1-Cer[OR(95%CI):1.522(1.136~.039),P<0.05]和LPC18∶0[OR(95%CI):1.198(1.102~1.302),P<0.001]是GDM的独立危险因素。ROC曲线分析结果显示,血清C18∶1-Cer,LPC18∶0和两指标联合的曲线下面积(area under the curve,AUC)分别为0.819,0.971和0.986,两者联合检测的预测效能优于单独检测。结论妊娠早期血清中的C18∶1-Cer和LPC18∶0与GDM的发生密切相关,C18∶1-Cer联合LPC18∶0对GDM早期诊断有一定的预测价值。
