目的分析丁苯酞序贯治疗急性脑梗死合并认知功能障碍患者的效果及心理状态的影响。方法抽取2020年9月~2022年9月期间本院进行治疗的160例急性脑梗死合并认知功能障碍患者作为研究对象,以“治疗不同方式”为基点平等划分为对照组、观察组...目的分析丁苯酞序贯治疗急性脑梗死合并认知功能障碍患者的效果及心理状态的影响。方法抽取2020年9月~2022年9月期间本院进行治疗的160例急性脑梗死合并认知功能障碍患者作为研究对象,以“治疗不同方式”为基点平等划分为对照组、观察组,各组收入80例,对照组实施丁苯酞静脉滴注疗法,观察组实施丁苯酞序贯治疗治疗,系统分析两组的临床效果、日常生活能力(Barthel)评分、神经功能缺损量表(NIHSS)评分、简易精神状态检查量表(Mini Mental State Examination,MMSE)评分、心理状态评分以及药物副作用发生率。结果治疗前,两组患者的Barthel指数、NIHSS评分、MMSE评分、心理状态评分无统计学差异(P>0.05);治疗后,对比于对照组,观察组患者的Barthel指数与MMSE评分显著较高,NIHSS评分、心理状态评分显著较低(P<0.05);治疗后,相较于对照组,观察组患者的临床效果显著较高(P<0.05);治疗后,相较于对照组,观察组患者的药物副作用发生率略微低,但差异无统计学意义(P>0.05)。结论合并认知功能障碍的急性脑梗死患者实施丁苯酞序贯治疗治疗可积极提升其治疗效果,改善神经功能缺损与认知功能程度,稳定心理状态,提高药物安全性。展开更多
OBJECTIVE:To observe the clinical efficacy of acupuncture along fascia,meridians,and nerves combined with ultrasound-guided nerve blockage in the treatment of postherpetic neuralgia.METHODS:A total of 61 outpatients w...OBJECTIVE:To observe the clinical efficacy of acupuncture along fascia,meridians,and nerves combined with ultrasound-guided nerve blockage in the treatment of postherpetic neuralgia.METHODS:A total of 61 outpatients with post-chest and back herpes zoster neuralgia were recruited in the Department of Pain at the Xiyuan Hospital,China Academy of Chinese Medical Sciences from May 2019 to June 2021.They were randomly divided into two groups.Thirty-one patients in the control group were treated with ultrasound-guided thoracic paravertebral nerve block(PVB)alone,one patient declined to continue during treatment(n=30),and thirty patients in the observation group received the acupuncture along the fascia,meridians,and nerves combined with ultrasound-guided PVB treatment(n=30).Both control and observation group received treatment weekly for 4 weeks.The medical history data such as age,sex,presence or absence of comorbidities and disease course were analyzed.The visual analog scale(VAS)score was used to assess the pain degree of two groups at T0(before treatment),T1(1-time treatment ended),T2(2 times treatment ended),T3(3 times treatment ended),and T4(4 times treatment ended).The sleep state was examined by Pittsburgh Sleep Quality Index(PSQI)before and after the study.RESULTS:There was no significant difference in general conditions between the control group and the observation group(P>0.05).The VAS score in both control and observation group was decreased in a time-dependent manner after 1-4 weeks of treatment.There were no significant differences in VAS scores between the two groups after 1 or 2 weeks of treatment(P>0.05).After 3 and 4 weeks of treatment,the VAS score was significantly decreased in the observation group compared with that in the control group(P<0.001).In addition,the reduction in VAS score(after treatment-before treatment)between the two groups was statistically significant[D value:-1.53,95%CI(-2.32,0.74),P<0.001].Furthermore,the sleep state of patients in both groups markedly improved and much obvious in the observation group than that in the control group(P<0.05).CONCLUSION:These results suggest that a combination of acupuncture along fascia,meridians,and nerves with ultrasound-guided PVB treatment is more effective than ultrasound-guided PVB treatment alone.展开更多
文摘目的分析丁苯酞序贯治疗急性脑梗死合并认知功能障碍患者的效果及心理状态的影响。方法抽取2020年9月~2022年9月期间本院进行治疗的160例急性脑梗死合并认知功能障碍患者作为研究对象,以“治疗不同方式”为基点平等划分为对照组、观察组,各组收入80例,对照组实施丁苯酞静脉滴注疗法,观察组实施丁苯酞序贯治疗治疗,系统分析两组的临床效果、日常生活能力(Barthel)评分、神经功能缺损量表(NIHSS)评分、简易精神状态检查量表(Mini Mental State Examination,MMSE)评分、心理状态评分以及药物副作用发生率。结果治疗前,两组患者的Barthel指数、NIHSS评分、MMSE评分、心理状态评分无统计学差异(P>0.05);治疗后,对比于对照组,观察组患者的Barthel指数与MMSE评分显著较高,NIHSS评分、心理状态评分显著较低(P<0.05);治疗后,相较于对照组,观察组患者的临床效果显著较高(P<0.05);治疗后,相较于对照组,观察组患者的药物副作用发生率略微低,但差异无统计学意义(P>0.05)。结论合并认知功能障碍的急性脑梗死患者实施丁苯酞序贯治疗治疗可积极提升其治疗效果,改善神经功能缺损与认知功能程度,稳定心理状态,提高药物安全性。
文摘OBJECTIVE:To observe the clinical efficacy of acupuncture along fascia,meridians,and nerves combined with ultrasound-guided nerve blockage in the treatment of postherpetic neuralgia.METHODS:A total of 61 outpatients with post-chest and back herpes zoster neuralgia were recruited in the Department of Pain at the Xiyuan Hospital,China Academy of Chinese Medical Sciences from May 2019 to June 2021.They were randomly divided into two groups.Thirty-one patients in the control group were treated with ultrasound-guided thoracic paravertebral nerve block(PVB)alone,one patient declined to continue during treatment(n=30),and thirty patients in the observation group received the acupuncture along the fascia,meridians,and nerves combined with ultrasound-guided PVB treatment(n=30).Both control and observation group received treatment weekly for 4 weeks.The medical history data such as age,sex,presence or absence of comorbidities and disease course were analyzed.The visual analog scale(VAS)score was used to assess the pain degree of two groups at T0(before treatment),T1(1-time treatment ended),T2(2 times treatment ended),T3(3 times treatment ended),and T4(4 times treatment ended).The sleep state was examined by Pittsburgh Sleep Quality Index(PSQI)before and after the study.RESULTS:There was no significant difference in general conditions between the control group and the observation group(P>0.05).The VAS score in both control and observation group was decreased in a time-dependent manner after 1-4 weeks of treatment.There were no significant differences in VAS scores between the two groups after 1 or 2 weeks of treatment(P>0.05).After 3 and 4 weeks of treatment,the VAS score was significantly decreased in the observation group compared with that in the control group(P<0.001).In addition,the reduction in VAS score(after treatment-before treatment)between the two groups was statistically significant[D value:-1.53,95%CI(-2.32,0.74),P<0.001].Furthermore,the sleep state of patients in both groups markedly improved and much obvious in the observation group than that in the control group(P<0.05).CONCLUSION:These results suggest that a combination of acupuncture along fascia,meridians,and nerves with ultrasound-guided PVB treatment is more effective than ultrasound-guided PVB treatment alone.
