目的评估小样本数据训练算法模型对于宫颈癌临床放疗中自动勾画的可行性。方法选取45例宫颈癌患者,由临床医生勾画临床靶区(Clinical Target Volume,CTV)及危及器官(Organs at Risk,OARs)。随机选择30例患者作为训练集传至AccuLearning...目的评估小样本数据训练算法模型对于宫颈癌临床放疗中自动勾画的可行性。方法选取45例宫颈癌患者,由临床医生勾画临床靶区(Clinical Target Volume,CTV)及危及器官(Organs at Risk,OARs)。随机选择30例患者作为训练集传至AccuLearning平台进行自主训练,训练好的算法模型传至AccuContour平台,对剩余15例患者进行自动勾画,分析新模型自动勾画与手动勾画的相似性系数(Dice Similarity Coefficient,DSC),敏感性指数(Sensitive Index,SI),质心偏差(Deviation of Centroid,DC)以及体积差异系数(Deviation of Volume,DV),评估自动勾画的可行性。结果各个结构的DSC均值均高于0.85;除了CTV的SI=0.87,其余的均≥0.90;CTV和肠袋的DC均值介于3~6 mm,其余的均<3 mm;关于DV指数,最小的是骨髓3.86%,最大的是肠袋12.32%。结论小样本数据训练算法模型对于宫颈癌CTV及OARs的勾画具有较高的准确性,能较好地辅助临床工作。展开更多
This paper presents the construction of Chinese hybrid radiation adult phantoms,which are compatible with anatomical parameters for the Chinese reference population.The phantoms were designed using polygonal mesh surf...This paper presents the construction of Chinese hybrid radiation adult phantoms,which are compatible with anatomical parameters for the Chinese reference population.The phantoms were designed using polygonal mesh surface,which makes the phantom more flexible and realistic than previous generations.Voxelization of hybrid phantoms was performed to adopt Monte Carlo methods.External dose coefficients were calculated by Geant4 and compared to the ICRP reference phantom.The results show that the organ dose is different from ICRP116 with the low energy photons,which can be ascribed to the anatomy and topology difference of each organ.The effective dose of CHRAP is 19%higher than ICRP 116 in the energy range from10 to 100 keV and is almost the same in the energy range from 100 keV to 10 MeV.These phantoms can be used as the basic phantom to adjust the posture or organ volume to estimate dosimetry in medical and space explorations.展开更多
文摘目的评估小样本数据训练算法模型对于宫颈癌临床放疗中自动勾画的可行性。方法选取45例宫颈癌患者,由临床医生勾画临床靶区(Clinical Target Volume,CTV)及危及器官(Organs at Risk,OARs)。随机选择30例患者作为训练集传至AccuLearning平台进行自主训练,训练好的算法模型传至AccuContour平台,对剩余15例患者进行自动勾画,分析新模型自动勾画与手动勾画的相似性系数(Dice Similarity Coefficient,DSC),敏感性指数(Sensitive Index,SI),质心偏差(Deviation of Centroid,DC)以及体积差异系数(Deviation of Volume,DV),评估自动勾画的可行性。结果各个结构的DSC均值均高于0.85;除了CTV的SI=0.87,其余的均≥0.90;CTV和肠袋的DC均值介于3~6 mm,其余的均<3 mm;关于DV指数,最小的是骨髓3.86%,最大的是肠袋12.32%。结论小样本数据训练算法模型对于宫颈癌CTV及OARs的勾画具有较高的准确性,能较好地辅助临床工作。
基金supported by the Fundamental Research Funds for the Central Universities(Grant No.NS2014060)
文摘This paper presents the construction of Chinese hybrid radiation adult phantoms,which are compatible with anatomical parameters for the Chinese reference population.The phantoms were designed using polygonal mesh surface,which makes the phantom more flexible and realistic than previous generations.Voxelization of hybrid phantoms was performed to adopt Monte Carlo methods.External dose coefficients were calculated by Geant4 and compared to the ICRP reference phantom.The results show that the organ dose is different from ICRP116 with the low energy photons,which can be ascribed to the anatomy and topology difference of each organ.The effective dose of CHRAP is 19%higher than ICRP 116 in the energy range from10 to 100 keV and is almost the same in the energy range from 100 keV to 10 MeV.These phantoms can be used as the basic phantom to adjust the posture or organ volume to estimate dosimetry in medical and space explorations.
