目的研究参附注射液联合布美他尼注射液治疗慢性充血性心力衰竭的临床疗效。方法选取2018年1月—2022年10月无锡市中医医院收治的90例充血性心力衰竭患者,通过随机数字表法将所有患者分为对照组和治疗组,每组各45例。对照组静脉滴注布...目的研究参附注射液联合布美他尼注射液治疗慢性充血性心力衰竭的临床疗效。方法选取2018年1月—2022年10月无锡市中医医院收治的90例充血性心力衰竭患者,通过随机数字表法将所有患者分为对照组和治疗组,每组各45例。对照组静脉滴注布美他尼注射液,2 mg置于250 mL 0.9%氯化钠注射液中稀释,滴注时间30~60 min,1次/d。治疗组在对照组基础上静脉滴注参附注射液,40 mL置于250 mL 5%葡萄糖注射液中稀释,滴注时间30~60 min,1次/d。两组患者均连续治疗10 d。观察两组的临床疗效,比较两组患者呼吸机辅助通气时间、心功能指标和血清脑钠肽(BNP)、N末端B型利尿钠肽原(NT-proBNP)。结果治疗后,治疗组的总有效率95.56%显著高于对照组的总有效率82.22%(P<0.05)。治疗后,治疗组无创呼吸辅助通气时间明显短于对照组,差异有统计学意义(P<0.05)。治疗后,两组左心室收缩末期内径(LVESD)、左心室收缩末期容积(LVESV)均较治疗前显著降低,左心室射血分数(LVEF)较治疗前明显升高(P<0.05),且治疗组LVESD、LVESV低于对照组,LVEF高于对照组,两组比较差异有统计学意义(P<0.05)。治疗后,两组血清BNP、NT-proBNP水平均较治疗前明显降低(P<0.05),且治疗组血清BNP、NT-proBNP水平明显低于对照组,两组比较差异有统计学意义(P<0.05)。结论参附注射液联合布美他尼注射液治疗充血性心力衰竭的疗效确切,可改善患者心功能,降低血清BNP、NT-proBNP水平,安全性良好。展开更多
Background Sexual and reproductive health among adolescents have become increasingly important and aroused international concerns. In this study, we investigate sexual knowledge, attitudes, sexual behaviors, the unwan...Background Sexual and reproductive health among adolescents have become increasingly important and aroused international concerns. In this study, we investigate sexual knowledge, attitudes, sexual behaviors, the unwanted pregnancy and the abortion rate and to explore related determinants among college students in Beijing. Methods This study is based on a cross-sectional survey of college students＇ knowledge, attitudes and behavior. Multistage cluster sampling was used to select subjects in Beijing. The self-questionnaire designed.by our research group including general information, knowledge, attitude and behavior about sexuality was used to collect information. A total of 2003 questionnaires were collected from June to July 2010. Results The data showed that most of the college students lacked knowledge about reproductive health. Only 17.9% of the respondents knew the appropriate time of abortion. Data also showed that the respondents had high-risk attitude about sex, 58.7% could accept premarital sex, and 29.7% had negative attitude towards contraception. Moreover, sexual activity of the respondents was active. Data showed that 18.5% of the respondents had had sexual activities. Significantly more boys than girls had sex （Х^2=73.374, P 〈0.001）. Among the boys and girls who reported sexual history, 43.1% of the boys had impregnated girlfriend and 49.3% of the girls among those people who have sex had unwanted pregnancies. Logistic regression analysis showed that the variables the gender （OR=3.12, 95% CI： 2.39-4.11）, grade （OR=1.78, 95% CI： 1.40-2.26）, specialty （OR=1.35, 95% CI： 1.12-1.74）, family situation （OR=1.66, 95% CI： 1.15-2.38）, score of knowledge （OR=0.74, 95% CI： 0.58-0.95） and attitude to sex activity （OR=0.09, 95% CI： 0.04-0.22） had a significant effect on having sexual behavior. Conclusions College students lack knowledge and methods students have high-risk sexual attitude and behaviors. Therefore college students would be strongly recommended. to avoid risky sexual behaviors in Beijing. College suitable and effective sex health measures to protect展开更多
文摘目的研究参附注射液联合布美他尼注射液治疗慢性充血性心力衰竭的临床疗效。方法选取2018年1月—2022年10月无锡市中医医院收治的90例充血性心力衰竭患者,通过随机数字表法将所有患者分为对照组和治疗组,每组各45例。对照组静脉滴注布美他尼注射液,2 mg置于250 mL 0.9%氯化钠注射液中稀释,滴注时间30~60 min,1次/d。治疗组在对照组基础上静脉滴注参附注射液,40 mL置于250 mL 5%葡萄糖注射液中稀释,滴注时间30~60 min,1次/d。两组患者均连续治疗10 d。观察两组的临床疗效,比较两组患者呼吸机辅助通气时间、心功能指标和血清脑钠肽(BNP)、N末端B型利尿钠肽原(NT-proBNP)。结果治疗后,治疗组的总有效率95.56%显著高于对照组的总有效率82.22%(P<0.05)。治疗后,治疗组无创呼吸辅助通气时间明显短于对照组,差异有统计学意义(P<0.05)。治疗后,两组左心室收缩末期内径(LVESD)、左心室收缩末期容积(LVESV)均较治疗前显著降低,左心室射血分数(LVEF)较治疗前明显升高(P<0.05),且治疗组LVESD、LVESV低于对照组,LVEF高于对照组,两组比较差异有统计学意义(P<0.05)。治疗后,两组血清BNP、NT-proBNP水平均较治疗前明显降低(P<0.05),且治疗组血清BNP、NT-proBNP水平明显低于对照组,两组比较差异有统计学意义(P<0.05)。结论参附注射液联合布美他尼注射液治疗充血性心力衰竭的疗效确切,可改善患者心功能,降低血清BNP、NT-proBNP水平,安全性良好。
文摘Background Sexual and reproductive health among adolescents have become increasingly important and aroused international concerns. In this study, we investigate sexual knowledge, attitudes, sexual behaviors, the unwanted pregnancy and the abortion rate and to explore related determinants among college students in Beijing. Methods This study is based on a cross-sectional survey of college students＇ knowledge, attitudes and behavior. Multistage cluster sampling was used to select subjects in Beijing. The self-questionnaire designed.by our research group including general information, knowledge, attitude and behavior about sexuality was used to collect information. A total of 2003 questionnaires were collected from June to July 2010. Results The data showed that most of the college students lacked knowledge about reproductive health. Only 17.9% of the respondents knew the appropriate time of abortion. Data also showed that the respondents had high-risk attitude about sex, 58.7% could accept premarital sex, and 29.7% had negative attitude towards contraception. Moreover, sexual activity of the respondents was active. Data showed that 18.5% of the respondents had had sexual activities. Significantly more boys than girls had sex （Х^2=73.374, P 〈0.001）. Among the boys and girls who reported sexual history, 43.1% of the boys had impregnated girlfriend and 49.3% of the girls among those people who have sex had unwanted pregnancies. Logistic regression analysis showed that the variables the gender （OR=3.12, 95% CI： 2.39-4.11）, grade （OR=1.78, 95% CI： 1.40-2.26）, specialty （OR=1.35, 95% CI： 1.12-1.74）, family situation （OR=1.66, 95% CI： 1.15-2.38）, score of knowledge （OR=0.74, 95% CI： 0.58-0.95） and attitude to sex activity （OR=0.09, 95% CI： 0.04-0.22） had a significant effect on having sexual behavior. Conclusions College students lack knowledge and methods students have high-risk sexual attitude and behaviors. Therefore college students would be strongly recommended. to avoid risky sexual behaviors in Beijing. College suitable and effective sex health measures to protect
