Thin transparent oxide conducting films(TCOFs)of titanium and gallium substituted zinc oxide(TGZO)were fabricated via radio frequency(RF)magnetron sputtering technique.The effects of RF power on electrical,linear and ...Thin transparent oxide conducting films(TCOFs)of titanium and gallium substituted zinc oxide(TGZO)were fabricated via radio frequency(RF)magnetron sputtering technique.The effects of RF power on electrical,linear and nonlinear optical characteristics were investigated by Hall tester,Ultraviolet(UV)-visible spectrophotometer and optical characterization method.The results indicate that RF power significantly influences the electrical and optical properties of the deposited films.As RF power raises,the resistivity and Urbach energy fall initially and then rise,while the figure of merit,mean visible transmittance and optical bandgap show the reverse variation trend.At RF power of 190 W,the TGZO sample exhibits the highest electro-optical properties,with the maximum figure of merit(1.14×10^(4)Ω-1∙cm^(-1)),mean visible transmittance(86.9%)and optical bandgap(3.50 eV),the minimum resistivity(6.26×10^(-4)Ω∙cm)and Urbach energy(174.23 meV).In addition,the optical constants of the deposited films were determined by the optical spectrum fitting method,and the RF power dependence of nonlinear optical properties was studied.It is observed that all the thin films exhibit normal dispersion characteristics in the visible region,and the nonlinear optical parameters are greatly affected by the RF power in the ultraviolet region.展开更多
目的:系统评价奥马珠单抗在儿童中重度过敏性哮喘治疗中的有效性和安全性。方法:计算机检索中国知网、万方数据库、PubMed、Cochrane Controlled Register of Trials(CENTRAL)及Embase数据库,检索时间均为建库至2021年3月,纳入奥马珠单...目的:系统评价奥马珠单抗在儿童中重度过敏性哮喘治疗中的有效性和安全性。方法:计算机检索中国知网、万方数据库、PubMed、Cochrane Controlled Register of Trials(CENTRAL)及Embase数据库,检索时间均为建库至2021年3月,纳入奥马珠单抗治疗儿童中重度过敏性哮喘的随机对照试验(研究组患儿使用奥马珠单抗治疗;对照组患儿使用其他治疗过敏性哮喘的药物或安慰剂),由2名评价员按纳入与排除标准筛选文献、提取资料,采用Rev Man 5.3软件进行荟萃分析(Meta分析)。结果:最终纳入8篇文献,包括1756例患儿。Meta分析结果显示,有效性方面,研究组患儿的哮喘恶化发生率(以恶化风险人日数表示恶化发生率:RR=0.68,95%CI=0.55~0.85,P=0.0007;以发生恶化患儿所占百分比表示恶化发生率:RR=0.54,95%CI=0.45~0.66,P<0.00001)显著低于对照组,哮喘全球疗效评估(GETE)优良率(RR=1.39,95%CI=1.23~1.58,P<0.00001)、儿童控制哮喘测试(C-ACT)评分(MD=0.76,95%CI=0.31~1.21,P=0.001)显著高于对照组,上述差异均有统计学意义;但两组患儿的第1秒用力呼气容积占预计值百分比(FEV_(1)%)(MD=0.62,95%CI=-0.89~2.13,P=0.42)、第1秒用力呼气容积占用力肺活量百分比(FEV_(1)/FVC)(MD=-0.10,95%CI=-0.98~0.79,P=0.83)比较,差异均无统计学意义。安全性方面,研究组患儿的严重不良事件发生率显著低于对照组(RR=0.54,95%CI=0.39~0.76,P=0.0004),缺课时间(MD=-0.30,95%CI=-0.57~-0.02,P=0.04)显著少于对照组,差异均有统计学意义。结论:奥马珠单抗可有效改善儿童中重度过敏性哮喘患者的临床指标,显著降低严重不良事件发生率,改善患儿的生活质量。展开更多
文摘Thin transparent oxide conducting films(TCOFs)of titanium and gallium substituted zinc oxide(TGZO)were fabricated via radio frequency(RF)magnetron sputtering technique.The effects of RF power on electrical,linear and nonlinear optical characteristics were investigated by Hall tester,Ultraviolet(UV)-visible spectrophotometer and optical characterization method.The results indicate that RF power significantly influences the electrical and optical properties of the deposited films.As RF power raises,the resistivity and Urbach energy fall initially and then rise,while the figure of merit,mean visible transmittance and optical bandgap show the reverse variation trend.At RF power of 190 W,the TGZO sample exhibits the highest electro-optical properties,with the maximum figure of merit(1.14×10^(4)Ω-1∙cm^(-1)),mean visible transmittance(86.9%)and optical bandgap(3.50 eV),the minimum resistivity(6.26×10^(-4)Ω∙cm)and Urbach energy(174.23 meV).In addition,the optical constants of the deposited films were determined by the optical spectrum fitting method,and the RF power dependence of nonlinear optical properties was studied.It is observed that all the thin films exhibit normal dispersion characteristics in the visible region,and the nonlinear optical parameters are greatly affected by the RF power in the ultraviolet region.
文摘目的:系统评价奥马珠单抗在儿童中重度过敏性哮喘治疗中的有效性和安全性。方法:计算机检索中国知网、万方数据库、PubMed、Cochrane Controlled Register of Trials(CENTRAL)及Embase数据库,检索时间均为建库至2021年3月,纳入奥马珠单抗治疗儿童中重度过敏性哮喘的随机对照试验(研究组患儿使用奥马珠单抗治疗;对照组患儿使用其他治疗过敏性哮喘的药物或安慰剂),由2名评价员按纳入与排除标准筛选文献、提取资料,采用Rev Man 5.3软件进行荟萃分析(Meta分析)。结果:最终纳入8篇文献,包括1756例患儿。Meta分析结果显示,有效性方面,研究组患儿的哮喘恶化发生率(以恶化风险人日数表示恶化发生率:RR=0.68,95%CI=0.55~0.85,P=0.0007;以发生恶化患儿所占百分比表示恶化发生率:RR=0.54,95%CI=0.45~0.66,P<0.00001)显著低于对照组,哮喘全球疗效评估(GETE)优良率(RR=1.39,95%CI=1.23~1.58,P<0.00001)、儿童控制哮喘测试(C-ACT)评分(MD=0.76,95%CI=0.31~1.21,P=0.001)显著高于对照组,上述差异均有统计学意义;但两组患儿的第1秒用力呼气容积占预计值百分比(FEV_(1)%)(MD=0.62,95%CI=-0.89~2.13,P=0.42)、第1秒用力呼气容积占用力肺活量百分比(FEV_(1)/FVC)(MD=-0.10,95%CI=-0.98~0.79,P=0.83)比较,差异均无统计学意义。安全性方面,研究组患儿的严重不良事件发生率显著低于对照组(RR=0.54,95%CI=0.39~0.76,P=0.0004),缺课时间(MD=-0.30,95%CI=-0.57~-0.02,P=0.04)显著少于对照组,差异均有统计学意义。结论:奥马珠单抗可有效改善儿童中重度过敏性哮喘患者的临床指标,显著降低严重不良事件发生率,改善患儿的生活质量。
