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Association between Ambient Air Pollution and Outpatient Visits for Acute Bronchitis in a Chinese City 被引量:13
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作者 guo li juan ZHAO Ang +2 位作者 CHEN Ren Jie KAN Hai Dong KUANG Xing Ya 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2014年第11期833-840,共8页
Objective To investigate the short-term association between outdoor air pollution and outpatient visits for acute bronchitis,which is a rare subject of research in the mainland of China.Methods A time-series analysis ... Objective To investigate the short-term association between outdoor air pollution and outpatient visits for acute bronchitis,which is a rare subject of research in the mainland of China.Methods A time-series analysis was conducted to examine the association of outdoor air pollutants with hospital outpatient visits in Shanghai by using two-year daily data(2010-2011).Results Outdoor air pollution was found to be associated with an increased risk of outpatient visits for acute bronchitis in Shanghai.The effect estimates of air pollutants varied with the lag structures of the concentrations of the pollutants.For lag06,a 10 μg/m3 increase in the concentrations of PM10,SO2,and NO2 corresponded to 0.94%(95% CI:0.83%,1.05%),11.12%(95% CI:10.76%,11.48%),and 4.84%(95% CI:4.49%,5.18%) increases in hospital visits for acute bronchitis,respectively.These associations appeared to be stronger in females(P〈0.05).Between-age differences were significant for SO2(P〈0.05),and between-season differences were also significant for SO2(P〈0.05).Conclusion Our analyses have provided the first evidence that the current air pollution level in China has an effect on acute bronchitis and that the rationale for further limiting air pollution levels in Shanghai should be strengthened. 展开更多
关键词 Air pollution Outpatient visits Acute bronchitis Time-series
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损伤相关分子模式在口腔恶性肿瘤中的研究进展
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作者 朱记涛 曹菲菲 +1 位作者 郭丽娟 杨森 《肿瘤预防与治疗》 2021年第9期874-880,共7页
目的:口腔恶性肿瘤的主要治疗方法包括手术、放化疗等。近年来,免疫治疗成为口腔恶性肿瘤治疗的新方法,免疫原性死亡的概念应运而生。口腔恶性肿瘤细胞经过放化疗后会发生凋亡,凋亡的细胞表面会释放一系列信号分子,这些信号分子促使机... 目的:口腔恶性肿瘤的主要治疗方法包括手术、放化疗等。近年来,免疫治疗成为口腔恶性肿瘤治疗的新方法,免疫原性死亡的概念应运而生。口腔恶性肿瘤细胞经过放化疗后会发生凋亡,凋亡的细胞表面会释放一系列信号分子,这些信号分子促使机体对肿瘤细胞发生强烈的免疫应答,此过程称为细胞免疫原性死亡(immunogenic death,ICD)。口腔恶性肿瘤细胞ICD是一个涉及多种信号分子的过程,这些免疫信号称为损伤相关分子模式,主要包括钙网蛋白、热休克蛋白、高迁移率族蛋白B1以及三磷酸腺苷,本文对其进行简要概述。 展开更多
关键词 免疫原性死亡 钙网蛋白 热休克蛋白 高迁移率蛋白B1 三磷酸腺苷
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