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Nanoskin®-ACT—The Impact of Natural Membrane & Soft with Chronic and Untreated Wounds
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作者 Saqer Al Mualla Noura Salim Salman +5 位作者 Salma Saeed Ns. Nasreen Abdelatif Mohamed Kanjou gabriel molina de olyveira Pierre Basmaji Antônio Carlos Guastaldi 《Journal of Biomaterials and Nanobiotechnology》 2024年第3期39-50,共12页
Bacterial cellulose (BC) is a versatile biomaterial with unique properties that make it promising for various biomedical applications, including wound healing. The extracellular matrix (ECM) plays a crucial role in wo... Bacterial cellulose (BC) is a versatile biomaterial with unique properties that make it promising for various biomedical applications, including wound healing. The extracellular matrix (ECM) plays a crucial role in wound healing, providing a structural scaffold and signaling cues for cell migration and proliferation. This study investigates the potential of BC as a scaffold for ECM production and its effect on in vivo wound healing. In this work, the bacterial cellulose fermentation process is modified by the addition of Green Propolis and Usnic acid to the culture medium and natural materials before the bacteria are inoculated. In vivo behaviour using natural membranes for regenerative medicine is presented and it is in edit. Overall, our findings demonstrate the potential of BC as a scaffold for ECM production and its beneficial effects on in vivo wound healing. BC-based dressings may offer a novel approach to promoting wound healing and tissue regeneration in clinical settings. Further studies are warranted to optimize BC-based therapies and explore their full potential in regenerative medicine. 展开更多
关键词 Bacterial Cellulose BIOMATERIALS NANOMEDICINE Wound Healing Green Propolis and Usnic Acid
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Novel LDPE/EVA Nanocomposites with Silver/Titanium Dioxide Particles for Biomedical Applications 被引量:1
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作者 gabriel molina de olyveira Ligia Maria Manzine Costa +2 位作者 Ant6nio Joss Felix de Carvalho Pierre Basmaji Luiz Antonio Pessan 《材料科学与工程(中英文B版)》 2011年第4期516-522,共7页
关键词 纳米复合材料 二氧化钛颗粒 LDPE 生物医学应用 EVA 含银 二氧化钛纳米粒子 聚乙烯复合材料
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Special Nanoskin-ACT-Biological Membranes from Deep Wounds
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作者 Saqer Al Mualla Mashael Al Nabooda +5 位作者 Noura Salim Salman Pierre Basmaji gabriel molina de olyveira Ligia Maria Manzine Costa Jose Domingos Da Costa Oliveira Gino Bruno Francozo 《Journal of Biomaterials and Nanobiotechnology》 2018年第1期79-88,共10页
Bacterial cellulose (BC) is established as a newest biomaterial, and it can be used for medical and odontology applications. In addition, it has called attention for uses such as membrane for wound care and tissue eng... Bacterial cellulose (BC) is established as a newest biomaterial, and it can be used for medical and odontology applications. In addition, it has called attention for uses such as membrane for wound care and tissue engineering. In this work, the bacterial cellulose fermentation process is modified by the addition of natural materials before the bacteria are inoculated. In vivo behavior using natural ECM for regenerative medicine is presented and completed wound healing process is 3 months. 展开更多
关键词 Bacterial Cellulose(Nanoskin^(█))&ACT(Advanced Cell Therapy) Natural Nanocomposites Tissue Engineering
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Skin Cancer Treatment by Nanoskin Cellulose: Future Cancer Wound Healing 被引量:1
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作者 Pierre Basmaji gabriel molina de olyveira Mohamed M. Kanjou 《Journal of Biomaterials and Nanobiotechnology》 2021年第1期1-6,共6页
<span style="font-family:Verdana;">Cancer cells can be proliferating in a few months and years</span><span style="font-family:Verdana;">.</span><span style="font-fam... <span style="font-family:Verdana;">Cancer cells can be proliferating in a few months and years</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;"> It depends </span><span style="font-family:Verdana;">on</span><span style="font-family:Verdana;"> cancer stage. Chemotherapy, immunotherapy and anti-metabolic drugs have been used in order to kill cancer cells and prevent immune system weakly and metastasis. However, such drugs can damage healthy cells too. Natural ways to cancer treatments may help whole body to cancer cells. In this work, it was taking off cancer nodule to skin cancer by surgery and we treat the nodule as wound, using Nanoskin</span><sup><span style="font-family:Verdana;"><sup></sup></span><span style="font-family:Verdana;background-color:#FFFFFF;"><sup><span style="font-family:Verdana, Helvetica, Arial;">&#174;</sup></span></span></sup><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"> advance cell therapy (ACT), natural extra cellular matrix which releases nutrients to the skin cancer. Our result shows that the cancer nodule disappear</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> in few weeks in skin, because of natural membrane treatment. In addition, we obtained complete wound healing due anticancer nutrients (beta-glucan) delivery to skin.</span> 展开更多
关键词 Nanoskin Cellulose Bacterial Cellulose Wound Healing Skin Cancer In Vivo Analysis
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Study of Nanoskin ECM-Bacterial Cellulose Wound Healing/United Arab Emirates 被引量:2
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作者 Saqer Al Mualla Raed Farahat +4 位作者 Pierre Basmaji gabriel molina de olyveira Ligia Maria Manzine Costa José Domingos da Costa Oliveira Gino Bruno Francozo 《Journal of Biomaterials and Nanobiotechnology》 2016年第2期109-117,共9页
Natural extracellular matrices (ECMs) perform the tasks necessary for tissue formation, maintenance, regulation and function, providing a powerful means of controlling the biological performance of regenerative materi... Natural extracellular matrices (ECMs) perform the tasks necessary for tissue formation, maintenance, regulation and function, providing a powerful means of controlling the biological performance of regenerative materials. In addition, biomedical materials have claimed attention because of the increased interest in tissue engineering materials for wound care and regenerative medicine. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization, cell support and Natural Extracellular Matrix (ECM) Scaffolds. In this work, we present the extracellular matrix (ECM) using the bacterial cellulose (Nanoskin<sup>®</sup>) which regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. Bacterial cellulose fermentation process is modified before the bacteria are inoculated for mimicking ECM to cells support and built new local material for wound healing. Chemical groups influences and thermal behavior in bacterial cellulose were analyzed using transmission infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA), respectively. Besides, In vivo analysis was evaluated with clinical study at Sharjah Kuwait Hospital. 展开更多
关键词 Bacterial Cellulose (Nanoskin) Natural Nanocomposites Regenerative Medicine Stem Cells
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Bacterial Cellulose for Several Medicine Areas: Future Insights
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作者 Pierre Basmaji gabriel molina de olyveira +1 位作者 Mohamed Kanjou Helena Reichert 《Journal of Biomaterials and Nanobiotechnology》 2022年第1期1-23,共23页
Bacterial cellulose (BC)-Nanoskin<span style="white-space:nowrap;"><sup><span style="white-space:nowrap;">&#174;</span></sup></span> has become established a... Bacterial cellulose (BC)-Nanoskin<span style="white-space:nowrap;"><sup><span style="white-space:nowrap;">&#174;</span></sup></span> has become established as a new biomaterial and can be used in several medicine areas, especially for medical devices mainly in dental and orthopedics applications. In addition, biomaterials have rise because of the increased interest in tissue engineering and regeneratine medicine materials for wound care and skin cancer treatment. The BC process production can be changed by different fermentation process. It has particular properties that make it an ideal candidate as a medical material: high mechanical properties, biocompatibility to the host tissue, and production in various shapes and sizes. This review describes a behavior investigation of this biomaterial in human medicine with bacterial cellulose, skin cancer, covid-19 and 3-D print for medical area. 展开更多
关键词 Bacterial Cellulose Biomaterial NANOTECHNOLOGIES
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3-D Print Celulose Nanoskin: Future Diabetic Wound Healing 被引量:2
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作者 Mohamed M. Kanjou Hassan Abdulhakim +1 位作者 gabriel molina de olyveira Pierre Basmaji 《Journal of Biomaterials and Nanobiotechnology》 2019年第4期190-195,共6页
3D printing is the future. It will change the way in which we produce new materials—maybe much less in factories and much easier in shops. However, biobased materials have been difficult to 3D print. Most 3D printers... 3D printing is the future. It will change the way in which we produce new materials—maybe much less in factories and much easier in shops. However, biobased materials have been difficult to 3D print. Most 3D printers use heat to melt the plastic or metal to be printed, and biobased materials are degraded. But cellulose nanofibrils have a solution to this problem: the printing paste is wet and dries out to a solid material. In this work, it was showed recent wound healing in Vinous Ulcer with kidney and other health complications using bacterial cellulose 3D print membranes. 展开更多
关键词 Bacterial Cellulose Natural Membrane DIABETIC ULCER WOUND HEALING 3D PRINT Tissue Regeneration
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Natural ECM-Bacterial Cellulose Wound Healing—Dubai Study 被引量:2
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作者 Safwat Mohd. El-Hoseny Pierre Basmaji +4 位作者 gabriel molina de olyveira Ligia Maria Manzine Costa Abdulwahid M. Alwahedi José Domingos da Costa Oliveira Gino Bruno Francozo 《Journal of Biomaterials and Nanobiotechnology》 2015年第4期237-246,共10页
Bacterial cellulose (BC) can be used in wide area of applied scientific, especially for tissue regeneration and regenerative medicine, lately, bacterial cellulose mats are used in the treatment of skin conditions such... Bacterial cellulose (BC) can be used in wide area of applied scientific, especially for tissue regeneration and regenerative medicine, lately, bacterial cellulose mats are used in the treatment of skin conditions such as burns and ulcers, because of the morphology of fibrous biopolymers serving as a support for cell proliferation, its pores allow gas exchange between the organism and the environment. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization, cell support and Natural Extracellular Matrix (ECM) Scaffolds. In this scope, Natural ECM is the ideal biological scaffold since it contains all the components of the tissue. The development of mimicking biomaterials and hybrid biomaterial can further advance directed cellular differentiation without specific induction. The extracellular matrix (ECM) contains several signals that are received by cell surface receptors and contribute to cell adhesion and cell fate which control cellular activities such as proliferation, migration and differentiation. As such, regenerative medicine studies often rely on mimicking the natural ECM to promote the formation of new tissue by host cells, and characterization of natural ECM components is vital for the development of new biomimetic approaches. In this work, the bacterial cellulose fermentation process is modified by the addition of vegetal stem cell to the culture medium and natural materials before the bacteria are inoculated. In vivo behavior using natural ECM for regenerative medicine is presented. 展开更多
关键词 Bacterial CELLULOSE (Nanoskin) NATURAL Nanocomposites REGENERATIVE Medicine Stem Cells
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Nanopores Structure in Electrospun Bacterial Cellulose
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作者 Ligia Maria Manzine Costa gabriel molina de olyveira +1 位作者 Pierre Basmaji Lauro Xavier Filho 《Journal of Biomaterials and Nanobiotechnology》 2012年第1期92-96,共5页
Bacterial cellulose (BC) has established to be a remarkably versatile biomaterial and can be used in wide variety of applied scientific endeavours, especially for medical devices, lately, bacterial cellulose mats are ... Bacterial cellulose (BC) has established to be a remarkably versatile biomaterial and can be used in wide variety of applied scientific endeavours, especially for medical devices, lately, bacterial cellulose mats are used in the treatment of skin conditions such as burns and ulcers, because of the morphology of fibrous biopolymers serving as a support for cell proliferation, its pores allow gas exchange between the organism and the environment. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization and cell support. In this work, we obtain first electrospun bacterial cellulose mats after chemical treatment and without conductive additives. With DMA/LiClmechanism dissolution, modified bacterial cellulose was easily electrospun in chloroform/acetone solvents in comparison with BC unmodified. FTIR peaks results are consistent with proposed interactions between cellulose and DMA/LiCl solvent system. 展开更多
关键词 BACTERIAL CELLULOSE ELECTROSPINNING DRUG and Cell Delivery.
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