To the Editor:Rheumatoid arthritis(RA)is an autoimmune disease characterized by invasive arthritis,affecting approximately 1%of the global population.Young and middle-aged women are prone to RA and can experience one ...To the Editor:Rheumatoid arthritis(RA)is an autoimmune disease characterized by invasive arthritis,affecting approximately 1%of the global population.Young and middle-aged women are prone to RA and can experience one or more pregnancies during the course of the disease.The developmental origins of health and disease describes how health hazards occurring at a young age could affect one’s health in later life.[1]RA exposure during pregnancy can consequently influence the health of the offspring.This paper discusses the pregnancy status of women with RA and the possible influence of RA on the health of the offspring.展开更多
To the Editor:The Human Genome Project decodes the mysteries of life,explores the pathogenesis of disease,and provides scientific evidence for the diagnosis and treatment of disease.Traditional sequencing methods pred...To the Editor:The Human Genome Project decodes the mysteries of life,explores the pathogenesis of disease,and provides scientific evidence for the diagnosis and treatment of disease.Traditional sequencing methods predominantly provide genome-wide sequence information and an average of the mix of cell types,which does not take into account the heterogeneity between cells and between subtypes.Advances in genome sequencing technology have allowed the development of single cell sequencing(SCS).展开更多
基金supported by grants from the National Natural Science Foundation(No.81771768)the Applied Basic Research Program of Shanxi Province(No.201801D221380)。
文摘To the Editor:Rheumatoid arthritis(RA)is an autoimmune disease characterized by invasive arthritis,affecting approximately 1%of the global population.Young and middle-aged women are prone to RA and can experience one or more pregnancies during the course of the disease.The developmental origins of health and disease describes how health hazards occurring at a young age could affect one’s health in later life.[1]RA exposure during pregnancy can consequently influence the health of the offspring.This paper discusses the pregnancy status of women with RA and the possible influence of RA on the health of the offspring.
基金This work was supported by grants from the National Natural Science Foundation of China(No.81871292)the Key Research and Development Projects of Shanxi Province(No.201803D31136)the Applied Basic Research Program of Shanxi Province(No.201901D111416)。
文摘To the Editor:The Human Genome Project decodes the mysteries of life,explores the pathogenesis of disease,and provides scientific evidence for the diagnosis and treatment of disease.Traditional sequencing methods predominantly provide genome-wide sequence information and an average of the mix of cell types,which does not take into account the heterogeneity between cells and between subtypes.Advances in genome sequencing technology have allowed the development of single cell sequencing(SCS).
