A series of sulpha/substituted derivatives of phenyl azo-1,2-diazole have been synthesized and tested as an anti-inflammatory and anti-bacterial activity in mature albino rats hind paw by taking Diclofenac sodium as s...A series of sulpha/substituted derivatives of phenyl azo-1,2-diazole have been synthesized and tested as an anti-inflammatory and anti-bacterial activity in mature albino rats hind paw by taking Diclofenac sodium as standard. N1-(4-hydroxy benzoyl)-3-methyl-5-phenyl-4(N-4-chlorophenylazo)-1,2-diazole is synthesized by a two-step process. In the first step, synthesis of N1-4-chlorophenyl hydrazono-1-methyl-3-phenyl propane-1,3-dione by the reciprocal action of 1-methyl-5-phenylpropane-1,3-dione and diazonium salt solution of phenyl-chloride interacts with 4-hydroxybenzoic acid hydrazide to form the final compound. These diazoles, the heterocyclic compounds which contained electron withdrawing groups, were screened for analgesic activity by acetic acid induced writing method, and for anti-inflammatory activity carried on carrageenan-induced paw edema. The synthesized substituted Chlorophenylazo-1,2-diazole nucleus exhibited significant anti-bacterial, anti-cancer, anti-inflammatory activity, muscle relaxing and moderate activity in anti-proliferative studies.展开更多
Using a simple combustion process, rare earth doped novel compounds like fluorides LiBF4 and Li3BF6 can be prepared. Combustion synthesis furnishes a quick method for preparation of these phosphors. The prepared phosp...Using a simple combustion process, rare earth doped novel compounds like fluorides LiBF4 and Li3BF6 can be prepared. Combustion synthesis furnishes a quick method for preparation of these phosphors. The prepared phosphors were characterized by the photoluminescence (PL) techniques. It is suggested that borofluoride based materials can be developed as low-cost phosphors. Formation of single phase compounds was confirmed by XRD. It is observed that prepared phosphors exhibited intense and characteristic Ce3+ and Eu2+ photoluminescence emission in blue visible region. This article summarizes fundamentals and possible applications of optically useful inorganic fluoride materials, with visible photoluminescence of Ce3+ and Eu2+ doped ions.展开更多
Tissue engineering is a well-proven technique for the creation of functional alternatives for regenerative medicine and plays a critical role in patient treatment.Several natural-origin biopolymers such as chitosan,hy...Tissue engineering is a well-proven technique for the creation of functional alternatives for regenerative medicine and plays a critical role in patient treatment.Several natural-origin biopolymers such as chitosan,hyaluronic acid,gelatin,collagen,etc.are extensively explored for various biomedical applications.Among,these polymers are exclusively investigated in tissue engineering applications due to their highly favorable properties,such as high biocompatibility,slow degradation,mechanical tenability,structural similarity with native tissues,bioactivity,etc.The present review summarizes the recent advances of biopolymers in bone tissue engineering It also covers the topic of natural polymer modification to achieve superior characteristics primarily mechanical properties towards bone regeneration and discussed the best methods for dealing with them.Therefore,the review can drive the development of biomimetic materials for futuristic applications.展开更多
文摘A series of sulpha/substituted derivatives of phenyl azo-1,2-diazole have been synthesized and tested as an anti-inflammatory and anti-bacterial activity in mature albino rats hind paw by taking Diclofenac sodium as standard. N1-(4-hydroxy benzoyl)-3-methyl-5-phenyl-4(N-4-chlorophenylazo)-1,2-diazole is synthesized by a two-step process. In the first step, synthesis of N1-4-chlorophenyl hydrazono-1-methyl-3-phenyl propane-1,3-dione by the reciprocal action of 1-methyl-5-phenylpropane-1,3-dione and diazonium salt solution of phenyl-chloride interacts with 4-hydroxybenzoic acid hydrazide to form the final compound. These diazoles, the heterocyclic compounds which contained electron withdrawing groups, were screened for analgesic activity by acetic acid induced writing method, and for anti-inflammatory activity carried on carrageenan-induced paw edema. The synthesized substituted Chlorophenylazo-1,2-diazole nucleus exhibited significant anti-bacterial, anti-cancer, anti-inflammatory activity, muscle relaxing and moderate activity in anti-proliferative studies.
文摘Using a simple combustion process, rare earth doped novel compounds like fluorides LiBF4 and Li3BF6 can be prepared. Combustion synthesis furnishes a quick method for preparation of these phosphors. The prepared phosphors were characterized by the photoluminescence (PL) techniques. It is suggested that borofluoride based materials can be developed as low-cost phosphors. Formation of single phase compounds was confirmed by XRD. It is observed that prepared phosphors exhibited intense and characteristic Ce3+ and Eu2+ photoluminescence emission in blue visible region. This article summarizes fundamentals and possible applications of optically useful inorganic fluoride materials, with visible photoluminescence of Ce3+ and Eu2+ doped ions.
文摘Tissue engineering is a well-proven technique for the creation of functional alternatives for regenerative medicine and plays a critical role in patient treatment.Several natural-origin biopolymers such as chitosan,hyaluronic acid,gelatin,collagen,etc.are extensively explored for various biomedical applications.Among,these polymers are exclusively investigated in tissue engineering applications due to their highly favorable properties,such as high biocompatibility,slow degradation,mechanical tenability,structural similarity with native tissues,bioactivity,etc.The present review summarizes the recent advances of biopolymers in bone tissue engineering It also covers the topic of natural polymer modification to achieve superior characteristics primarily mechanical properties towards bone regeneration and discussed the best methods for dealing with them.Therefore,the review can drive the development of biomimetic materials for futuristic applications.
