Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic.A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia,odynophagia and fe...Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic.A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia,odynophagia and fever.Esophagogastroduodenoscopy(EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm.Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm,multinucleated and faceted nuclei with glassy chromatin,and an occasional Cowdry type A intranuclear inclusion bodies.Few candidal spores were seen in the underlying stroma.Intravenous acyclovir,fluconazole and pantoprazole were initiated.Oral analgesics were given for pain relief.She was treated for a total of 14 days.She showed significant improvement and was tolerating oral intake after discharge.The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.展开更多
文摘Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic.A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia,odynophagia and fever.Esophagogastroduodenoscopy(EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm.Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm,multinucleated and faceted nuclei with glassy chromatin,and an occasional Cowdry type A intranuclear inclusion bodies.Few candidal spores were seen in the underlying stroma.Intravenous acyclovir,fluconazole and pantoprazole were initiated.Oral analgesics were given for pain relief.She was treated for a total of 14 days.She showed significant improvement and was tolerating oral intake after discharge.The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.
