目的:分析我国南北方多囊卵巢综合征(PCOS)不孕患者临床基线特征及疗效的差异,从而为不同地域女性预防与治疗PCOS提供指导。方法:以秦岭-淮河线将644例PCOS患者按就诊医院分为北方和南方,随机给予小檗碱、来曲唑或小檗碱联合来曲唑治疗...目的:分析我国南北方多囊卵巢综合征(PCOS)不孕患者临床基线特征及疗效的差异,从而为不同地域女性预防与治疗PCOS提供指导。方法:以秦岭-淮河线将644例PCOS患者按就诊医院分为北方和南方,随机给予小檗碱、来曲唑或小檗碱联合来曲唑治疗,配合超声监测排卵,疗程共6个月。观察南北方PCOS受试者临床基线特征及疗效的差异。结果:南方P C O S受试者年龄,身高,体质量,腰围,臀围,身体质量指数,左、右卵巢体积,孕酮,促黄体生成素/促卵泡生成素,游离睾酮指数,胰岛素浓度等显著低于北方PCOS受试者(P<0.01);左、右侧窦卵泡数,促卵泡生成素,性激素结合球蛋白水平,抗苗勒管激素显著高于北方PCOS受试者(P<0.05,P<0.01);南北方PCOS受试者的排卵率、受孕率、妊娠率、流产率及活产率差异均无统计学意义。结论:北方受试者的PCOS病情重于南方受试者,地域差异及病情严重程度对促排卵药物疗效及生殖结局没有明显影响。展开更多
Objective This article aims to introduce the benefits of qualitative research and to discuss how such research can be applied to the study of polycystic ovary syndrome （PCOS）. Data sources Relevant articles were pub...Objective This article aims to introduce the benefits of qualitative research and to discuss how such research can be applied to the study of polycystic ovary syndrome （PCOS）. Data sources Relevant articles were published in English as of May 2013 from Pubmed. Terms ＂polycystic ovary syndrome/PCOS, qualitative research and methodology＂ were used for searching. Study selection Articles studying PCOS with qualitative methods were reviewed. Articles associated with the use of qualitative research in clinical research were cited. Results Six qualitative studies related to PCOS were found in the literature search. These studies addressed different aspects in PCOS women including their womanhood, lived experience, information need, and experience of treatment with acupuncture. Five of these six studies used phenomenology as guiding theory. Conclusion Quantitative research has been the dominant approach in the field so far, qualitative research is relevant to the advancement of PCOS.展开更多
文摘目的:分析我国南北方多囊卵巢综合征(PCOS)不孕患者临床基线特征及疗效的差异,从而为不同地域女性预防与治疗PCOS提供指导。方法:以秦岭-淮河线将644例PCOS患者按就诊医院分为北方和南方,随机给予小檗碱、来曲唑或小檗碱联合来曲唑治疗,配合超声监测排卵,疗程共6个月。观察南北方PCOS受试者临床基线特征及疗效的差异。结果:南方P C O S受试者年龄,身高,体质量,腰围,臀围,身体质量指数,左、右卵巢体积,孕酮,促黄体生成素/促卵泡生成素,游离睾酮指数,胰岛素浓度等显著低于北方PCOS受试者(P<0.01);左、右侧窦卵泡数,促卵泡生成素,性激素结合球蛋白水平,抗苗勒管激素显著高于北方PCOS受试者(P<0.05,P<0.01);南北方PCOS受试者的排卵率、受孕率、妊娠率、流产率及活产率差异均无统计学意义。结论:北方受试者的PCOS病情重于南方受试者,地域差异及病情严重程度对促排卵药物疗效及生殖结局没有明显影响。
文摘Objective This article aims to introduce the benefits of qualitative research and to discuss how such research can be applied to the study of polycystic ovary syndrome （PCOS）. Data sources Relevant articles were published in English as of May 2013 from Pubmed. Terms ＂polycystic ovary syndrome/PCOS, qualitative research and methodology＂ were used for searching. Study selection Articles studying PCOS with qualitative methods were reviewed. Articles associated with the use of qualitative research in clinical research were cited. Results Six qualitative studies related to PCOS were found in the literature search. These studies addressed different aspects in PCOS women including their womanhood, lived experience, information need, and experience of treatment with acupuncture. Five of these six studies used phenomenology as guiding theory. Conclusion Quantitative research has been the dominant approach in the field so far, qualitative research is relevant to the advancement of PCOS.
