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IgA肾病合并抑郁状态患者的临床特征和预后影响因素分析
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作者 高秦宇 包蓓艳 +1 位作者 金燕 赵宇 《临床荟萃》 CAS 2023年第6期510-515,共6页
目的分析IgA肾病合并抑郁状态患者的临床特征和预后影响因素。方法选取2019年112月于宁波市鄞州第二医院肾内科就诊的IgA肾病患者100例,根据是否合并抑郁状态分为对照组和观察组,每组各50例。分析两组一般资料、实验室指标及病理分型等... 目的分析IgA肾病合并抑郁状态患者的临床特征和预后影响因素。方法选取2019年112月于宁波市鄞州第二医院肾内科就诊的IgA肾病患者100例,根据是否合并抑郁状态分为对照组和观察组,每组各50例。分析两组一般资料、实验室指标及病理分型等临床特征。采用Kaplan-Meier法评估总生存期(OS),采用Logistics回归分析患者的预后影响因素。结果两组病程、工作状态、家庭人均月收入、肾小球滤过率(eGFR)、血红蛋白、血清白蛋白、血尿酸(SUA)、C3水平,以及炎细胞浸润程度和血管损伤程度比较,差异有统计学意义(P<0.01)。与对照组比较,观察组病程较长、多为非在职人员,且家庭人均月收入明显偏低。与对照组比较,观察组肾小球滤过率(eGFR)、血红蛋白、血清白蛋白水平降低,血尿酸(SUA)、C3水平升高,炎细胞浸润程度和血管损伤程度明显加重(P<0.05)。Logistic回归分析结果显示,病程、家庭人均月收入、eGFR、血红蛋白、血清白蛋白、炎细胞浸润程度及血管损伤程度是IgA肾病患者合并抑郁状态的独立影响因素(P<0.05)。将血肌酐水平翻倍和(或)进展为ESRD和(或)接受肾替代治疗和/或死亡设置为复合终点事件,截至3年随访期结束,12名例发生终点事件,其中观察组9例和对照组3例。观察组1年和3年OS率分别为94.00%和82.00%,对照组1年和3年OS率分别为98.00%和94.00%,两组3年OS比较,差异有统计学意义(P=0.034)。结论IgA肾病合并抑郁状态的独立危险因素包括病程、家庭人均月收入、eGFR、血红蛋白、血清白蛋白、炎细胞浸润程度及血管损伤程度,且IgA肾病合并抑郁状态患者的生存期明显下降。 展开更多
关键词 肾小球肾炎 IgA 抑郁 预后 病理分型 临床特征
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Development and Veri cation of the System Analysis Code IMPC-transient
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作者 Chen Kang Yang Yongwei +1 位作者 gao Yucui gao qinyu 《IMP & HIRFL Annual Report》 2017年第1期196-197,共2页
Introduction of IMPC-transient IMPC-transient is a system analysis code developed by RMPC group(Group of Reactor multi-physics Coupling)with Fortran language.It is suitable for critical and sub-critical fast reactors.... Introduction of IMPC-transient IMPC-transient is a system analysis code developed by RMPC group(Group of Reactor multi-physics Coupling)with Fortran language.It is suitable for critical and sub-critical fast reactors.A series of physical and mathematic models were established in this code.These models include the component model for reactor,the pump model,the heat exchanger model,then pipe model and the plenum model,etc.As to the neutronic model,the thermal-hydraulic code is coupled with DAISY in which either the transport kinetics model or the point kinetics model can be called.Figure.1 shows the typical primary loop computational model of IMPC-transient. 展开更多
关键词 language. TRANSIENT FORTRAN
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Primliminary Verification Calculation of the Target Design of XADS
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作者 Yang Yongwei Meng Haiyan +6 位作者 Shu Yafeng Fan Deliang gao Yucui gao qinyu Zhao Zelong Chen Kang Fang Peng 《IMP & HIRFL Annual Report》 2017年第1期189-191,共3页
1.MCNPX target physics computation The purpose of physical check is mainly to check whether the parameters in the XADS reports[1]are reasonable,to give the results and analysis and get the energy distribution of the t... 1.MCNPX target physics computation The purpose of physical check is mainly to check whether the parameters in the XADS reports[1]are reasonable,to give the results and analysis and get the energy distribution of the target window and target zone,so as to provide heat source for thermal engineering and structure.According to the reference,the proton beam energy is 600 MeV and the beam current is 6 mA.The footprint of the beam has a circular shape with the radius of 8 cm and the beam intensity following an elliptical radical distribution is given.The thickness of target window and beam tube is 3 mm,and the thickness of structural material is 5 mm,and the spherical radius of target window is 10 cm.Heavy metal material is LBE.All physical check calculations are accomplished by MCNPX2.7.0.The final physical results are showed in Table 1. 展开更多
关键词 structure. RADIUS BEAM
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