Depression is a serious health condition affecting an estimate of 350 million people worldwide.Monotherapy with antidepressants as first line treatment however is found to have limited benefits as compared to augmenta...Depression is a serious health condition affecting an estimate of 350 million people worldwide.Monotherapy with antidepressants as first line treatment however is found to have limited benefits as compared to augmentation therapy.Psychoactive agents such as caffeine,when added to the antidepressants are found to have positive effects with depression by acting as an antagonist to adenosine receptors.Male Swiss albino mice were grouped into six,first three groups with arbitrary doses of the combination of mirtazapine and caffeine and last three control groups being the untreated,mirtazapine-treated and caffeine-treated groups.展开更多
文摘Depression is a serious health condition affecting an estimate of 350 million people worldwide.Monotherapy with antidepressants as first line treatment however is found to have limited benefits as compared to augmentation therapy.Psychoactive agents such as caffeine,when added to the antidepressants are found to have positive effects with depression by acting as an antagonist to adenosine receptors.Male Swiss albino mice were grouped into six,first three groups with arbitrary doses of the combination of mirtazapine and caffeine and last three control groups being the untreated,mirtazapine-treated and caffeine-treated groups.
