Hypomorphic mutations of the nuclear factor κB essential modulator gene cause ectodermal dysplasia and immunodeficiency. Affected patients have increased susceptibility to mycobacterial disease including cutaneous ma...Hypomorphic mutations of the nuclear factor κB essential modulator gene cause ectodermal dysplasia and immunodeficiency. Affected patients have increased susceptibility to mycobacterial disease including cutaneous manifestations. We describe clinical and histopathologic characteristics of 5 patients with nuclear factor κB essential modulator gene mutations and mycobacterial infections, two of whom had mycobacterial cutaneous infections.展开更多
文摘Hypomorphic mutations of the nuclear factor κB essential modulator gene cause ectodermal dysplasia and immunodeficiency. Affected patients have increased susceptibility to mycobacterial disease including cutaneous manifestations. We describe clinical and histopathologic characteristics of 5 patients with nuclear factor κB essential modulator gene mutations and mycobacterial infections, two of whom had mycobacterial cutaneous infections.
