Tilapia were exposed to sub-lethal concentrations of 0, 0.2, 2, 20 or 200 μg/L for 30 d, and then transferred to methomyl-free water for 18 d. CAT and SOD in tilapia serum were examined at 0, 6, 12, 18, 24 and 30 d a...Tilapia were exposed to sub-lethal concentrations of 0, 0.2, 2, 20 or 200 μg/L for 30 d, and then transferred to methomyl-free water for 18 d. CAT and SOD in tilapia serum were examined at 0, 6, 12, 18, 24 and 30 d after methomyl exposure and at 18 d after transferring to methomyl-free water. There were no significant changes in antioxidants activities in tilapia exposed to 0.2 μg/L. Significant increases in SOD, CAT were observed following methomyl exposure to 2, 20 or 200 μg/L, suggesting the presence of oxidative stress. Thus, the 0.2 μg/L methomyl might be considered the no observed adverse effect level. Recovery data showed that the effects produced by lower concentration of 20 μg/L were reversible but not at the higher concentration of 200 μg/L.展开更多
基金Supported by the Special Scientific Research Funds for Central Non-profit Institutes,Chinese Academy of Fishery Sciences(No.2015C02XK01)the Natural Science Foundation of Jiangsu Province for Youth(No.BK20150117)the China Agriculture Research System(CARS-46)
文摘Tilapia were exposed to sub-lethal concentrations of 0, 0.2, 2, 20 or 200 μg/L for 30 d, and then transferred to methomyl-free water for 18 d. CAT and SOD in tilapia serum were examined at 0, 6, 12, 18, 24 and 30 d after methomyl exposure and at 18 d after transferring to methomyl-free water. There were no significant changes in antioxidants activities in tilapia exposed to 0.2 μg/L. Significant increases in SOD, CAT were observed following methomyl exposure to 2, 20 or 200 μg/L, suggesting the presence of oxidative stress. Thus, the 0.2 μg/L methomyl might be considered the no observed adverse effect level. Recovery data showed that the effects produced by lower concentration of 20 μg/L were reversible but not at the higher concentration of 200 μg/L.
