目的探讨急性心肌梗死患者术后运动恐惧水平现状,并分析相关影响因素。方法选择医院2021年1月—2023年1月收治的106例急性心肌梗死患者为调查对象,采用一般资料调查表、心脏病患者运动恐惧量表(The Tampa Scale for Kinesiophobia Heart...目的探讨急性心肌梗死患者术后运动恐惧水平现状,并分析相关影响因素。方法选择医院2021年1月—2023年1月收治的106例急性心肌梗死患者为调查对象,采用一般资料调查表、心脏病患者运动恐惧量表(The Tampa Scale for Kinesiophobia Heart,TSK-SV Heart)进行现状调查,采用单因素分析和多元线性回归分析影响患者运动恐惧水平的相关因素。结果调查结果显示,急性心肌梗死患者运动恐惧总分为46.30±6.15分,其中各维度按照得分由高到低排序为运动回避14.52±2.83分、运动恐惧12.42±2.76分、功能紊乱9.71±1.57分、危险感知9.65±1.58分;单因素分析结果显示,年龄、职业、是否合并心衰、术后时间、主要照护者、有无合并症、疼痛评分均为影响急性心肌梗死术后患者运动恐惧的相关因素(P<0.05);多元线性回归分析显示,年龄、是否合并心衰、术后时间、主要照护者、疼痛评分为急性心肌梗死术后患者运动恐惧的影响因素(P<0.05)。结论急性心肌梗死患者术后运动恐惧水平得分高于临界值,高龄、合并心衰、术后时间短、无或主要照护者为护工、疼痛评分高的急性心肌梗死患者更易发生运动恐惧,提示临床医护人员应重视急性心肌梗死患者术后心理体验,并加强运动恐惧水平的评估,从以上因素出发制订针对性改善与管理策略,以提高急性心肌梗死患者自我效能,帮助其克服运动恐惧,从而提高康复效果。展开更多
为了认识痕量元素As在飞灰中的富集特性,利用密度泛函理论研究了砷的典型氧化物AsO在飞灰中的主要成分SiO_2模型上的吸附机理,对优化后的吸附构型进行能量计算、AIM理论、Mulliken电荷分析以及定域化轨道指示函数(LOL)填色图分析,剖析了...为了认识痕量元素As在飞灰中的富集特性,利用密度泛函理论研究了砷的典型氧化物AsO在飞灰中的主要成分SiO_2模型上的吸附机理,对优化后的吸附构型进行能量计算、AIM理论、Mulliken电荷分析以及定域化轨道指示函数(LOL)填色图分析,剖析了AsO与SiO_2表面的相互作用。结果表明,AsO在无定型SiO_2表面的缺陷位的吸附能均大于50 k J/mol,吸附构型均为典型的化学吸附。在无定型SiO_2缺陷活性位点形成的As-Si键、Si-O键和As-O键强度较大,均属于共价键;SiO_2与AsO之间为共价相互作用。展开更多
According to the investigated data of Jiaozhou Bay in April, August, September and October of 1989, distribution, source and seasonal change of HCH in Jiaozhou Bay were analyzed. Results showed that HCH content change...According to the investigated data of Jiaozhou Bay in April, August, September and October of 1989, distribution, source and seasonal change of HCH in Jiaozhou Bay were analyzed. Results showed that HCH content changed during 0.012 7 -0.069 8 gg/L in Jiaozhou Bay and was very low. Seen from HCH content, water in Jiaozhou Bay was cleaner, and HCH did not have seasonal change. Horizontal distribution of HCH showed that HCH was directly input into offshore water only by surface runoff, and there was no river input. HCH was area source and was from land. In Jiaozhou Bay, the maximum HCH was gradually becoming smaller, and input manner also changed. HCH migration changed from river input to river and surface runoff input to final surface runoff input.展开更多
Sophorae Flavescentis Radix(SFR)is a medicinal herb with many functions that are involved in anti-inflammation,antinociception,and anticancer.SFR is also used to treat a variety of itching diseases.Matrine(MT)is one o...Sophorae Flavescentis Radix(SFR)is a medicinal herb with many functions that are involved in anti-inflammation,antinociception,and anticancer.SFR is also used to treat a variety of itching diseases.Matrine(MT)is one of the main constituents in SFR and also has the effect of relieving itching,but the antipruritic mechanism is still unclear.Here,we investigated the effect of MT on antipruritus.In acute and chronic itch models,MT significantly inhibited the scratching behavior not only in acute itching induced by histamine(His),chloroquine(CQ)and compound 48/80 with a dose-depended manner,but also in the chronic pruritus models of Atopic dermatitis(AD)and Acetone-ether-water(AEW)in mice.Furthermore,MT can be detected in the blood after intraperitoneal injection(i.p.)and subcutaneous injection(s.c.).Finally,electrophysiological and calcium image results show that MT inhibits the excitatory synaptic transmission from dorsal root ganglion(DRG)to the dorsal horn of the spinal cord by suppressing presynaptic N-type calcium channels.Taken together,we believe that MT is a novel drug candidate in treating pruritus diseases,especially for histamine-independent and chronic pruritus,which might be attributed to inhibition of presynaptic N-type calcium channels.展开更多
文摘目的探讨急性心肌梗死患者术后运动恐惧水平现状,并分析相关影响因素。方法选择医院2021年1月—2023年1月收治的106例急性心肌梗死患者为调查对象,采用一般资料调查表、心脏病患者运动恐惧量表(The Tampa Scale for Kinesiophobia Heart,TSK-SV Heart)进行现状调查,采用单因素分析和多元线性回归分析影响患者运动恐惧水平的相关因素。结果调查结果显示,急性心肌梗死患者运动恐惧总分为46.30±6.15分,其中各维度按照得分由高到低排序为运动回避14.52±2.83分、运动恐惧12.42±2.76分、功能紊乱9.71±1.57分、危险感知9.65±1.58分;单因素分析结果显示,年龄、职业、是否合并心衰、术后时间、主要照护者、有无合并症、疼痛评分均为影响急性心肌梗死术后患者运动恐惧的相关因素(P<0.05);多元线性回归分析显示,年龄、是否合并心衰、术后时间、主要照护者、疼痛评分为急性心肌梗死术后患者运动恐惧的影响因素(P<0.05)。结论急性心肌梗死患者术后运动恐惧水平得分高于临界值,高龄、合并心衰、术后时间短、无或主要照护者为护工、疼痛评分高的急性心肌梗死患者更易发生运动恐惧,提示临床医护人员应重视急性心肌梗死患者术后心理体验,并加强运动恐惧水平的评估,从以上因素出发制订针对性改善与管理策略,以提高急性心肌梗死患者自我效能,帮助其克服运动恐惧,从而提高康复效果。
文摘为了认识痕量元素As在飞灰中的富集特性,利用密度泛函理论研究了砷的典型氧化物AsO在飞灰中的主要成分SiO_2模型上的吸附机理,对优化后的吸附构型进行能量计算、AIM理论、Mulliken电荷分析以及定域化轨道指示函数(LOL)填色图分析,剖析了AsO与SiO_2表面的相互作用。结果表明,AsO在无定型SiO_2表面的缺陷位的吸附能均大于50 k J/mol,吸附构型均为典型的化学吸附。在无定型SiO_2缺陷活性位点形成的As-Si键、Si-O键和As-O键强度较大,均属于共价键;SiO_2与AsO之间为共价相互作用。
基金Supported by Science Research Special Item of Marine Public Service Sectors,China(201205012,201305012)Science Research Fund of Director in North China Sea Environmental Monitoring Center of State Oceanic Administration,China(05EMC16)
文摘According to the investigated data of Jiaozhou Bay in April, August, September and October of 1989, distribution, source and seasonal change of HCH in Jiaozhou Bay were analyzed. Results showed that HCH content changed during 0.012 7 -0.069 8 gg/L in Jiaozhou Bay and was very low. Seen from HCH content, water in Jiaozhou Bay was cleaner, and HCH did not have seasonal change. Horizontal distribution of HCH showed that HCH was directly input into offshore water only by surface runoff, and there was no river input. HCH was area source and was from land. In Jiaozhou Bay, the maximum HCH was gradually becoming smaller, and input manner also changed. HCH migration changed from river input to river and surface runoff input to final surface runoff input.
文摘Sophorae Flavescentis Radix(SFR)is a medicinal herb with many functions that are involved in anti-inflammation,antinociception,and anticancer.SFR is also used to treat a variety of itching diseases.Matrine(MT)is one of the main constituents in SFR and also has the effect of relieving itching,but the antipruritic mechanism is still unclear.Here,we investigated the effect of MT on antipruritus.In acute and chronic itch models,MT significantly inhibited the scratching behavior not only in acute itching induced by histamine(His),chloroquine(CQ)and compound 48/80 with a dose-depended manner,but also in the chronic pruritus models of Atopic dermatitis(AD)and Acetone-ether-water(AEW)in mice.Furthermore,MT can be detected in the blood after intraperitoneal injection(i.p.)and subcutaneous injection(s.c.).Finally,electrophysiological and calcium image results show that MT inhibits the excitatory synaptic transmission from dorsal root ganglion(DRG)to the dorsal horn of the spinal cord by suppressing presynaptic N-type calcium channels.Taken together,we believe that MT is a novel drug candidate in treating pruritus diseases,especially for histamine-independent and chronic pruritus,which might be attributed to inhibition of presynaptic N-type calcium channels.
