高加索青少年双眼视网膜各指标的不对称性（英文）

目的:检查一组正常青少年高加索人群视网膜各项指标,以确定该年龄段和种族群体双眼之间不对称性的正常范围。方法:所研究人群包含37名高加索儿童和青少年,年龄12~23岁,等效球镜-3.00D^+4.00D,屈光参差<0.5D,两眼之间眼轴差<0.3mm。检测正常两眼各指标之间不对称性数值和两眼之间差异容许值的95%范围。结果:所有受试者左眼检测数值更大,两眼之间平均视网膜神经纤维(RNFL)厚度和上方RNFL厚度差异有统计学意义(P=0.003,0.008),中央黄斑厚度也存在显著差异(P=0.039)。检测得出以上三项两眼之间不对称性容许范围分别-9.00~6.00μm、-28.00~9μm、-39.00~29.00μm。此外,男性和女性之间右眼平均RNFL厚度的差异有统计学意义(P=0.020)。结论:两眼之间视网膜检测数值不对称性正常范围的研究可能是更进一步了解近视发生和发展的有效方法。这对于该年龄段的人群十分重要。检测仪器和检测人群特征的不同限制了研究结果和已发表文献的直接比较,需要进一步研究。

Role of microfluctuations in accommodation: a novel approach to reduce non-accommodative noise

Accommodative response and its possible role in myopia development has been explored through the study of the microfluctuations(MFs) of accommodation, which are commonly divided in high(1.0 to 2.3 Hz) and low(0.1 to 0.6 Hz) frequency components. Previous research efforts have evidenced that a certain percentage of the amplitude of MFs seems not to originate in the accommodative response. We aimed to develop and test a new approach to reduce this non-accommodative noise. For this purpose, ten healthy participants were enrolled to determine the difference between the amplitude of MFs at near and distance for each range of frequencies, which was defined as the relative amplitude of MFs. The findings support the exploration of the relative rather than absolute values of the amplitude of MFs to better understand the contribution of both accommodative and non-accommodative factors to MFs.