期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
The emerging epigenetics of PARK7 and its implication in neurodegenerative disease
1
作者 george d.vavougios Sotirios G.Zarogiannis 《Neural Regeneration Research》 SCIE CAS CSCD 2018年第9期1542-1543,共2页
PARK7/DJ-1 is a multifunctional protein that acts as a regulator in stress responsive cascades.Since its original discovery as a novel oncogene,DJ-1 was further implicated in the correspondingly dubbed PARK7 autosomal... PARK7/DJ-1 is a multifunctional protein that acts as a regulator in stress responsive cascades.Since its original discovery as a novel oncogene,DJ-1 was further implicated in the correspondingly dubbed PARK7 autosomal recessive early onset Parkinson’s Disease variant,expanding the spectrum of its pathophysiologyto neurodegenerative disease. 展开更多
关键词 The emerging epigenetics of PARK7 and its implication in neurodegenerative disease
下载PDF
Athletes with mild post-COVID-19 symptoms experience increased respiratory and metabolic demands:А cross-sectional study
2
作者 Vasileios T.Stavrou Astara Kyriaki +7 位作者 george d.vavougios Ioannis G.Fatouros george S.Metsios Konstantinos Kalabakas Dimitrios Karagiannis Zoe Daniil Konstantinos I.Gourgoulianis george Вasdekis 《Sports Medicine and Health Science》 2023年第2期106-111,共6页
Coronavirus Disease 2019(COVID-19)has significantly affected different physiological systems,with a potentially profound effect on athletic performance.However,to date,such an effect has been neither addressed nor inv... Coronavirus Disease 2019(COVID-19)has significantly affected different physiological systems,with a potentially profound effect on athletic performance.However,to date,such an effect has been neither addressed nor investigated.Therefore,the aim of this study was to investigate fitness indicators,along with the respiratory and metabolic profile,in post-COVID-19 athletes.Forty male soccer players,were divided into two groups:non-hospitalized COVID-19(n=20,Age:[25.2±4.1]years,Body Surface Area[BSA]:[1.9±0.2]m^(2),body fat:11.8%±3.4%)versus[vs]healthy(n=20,Age:[25.1±4.4]years,BSA:[2.0±0.3]m^(2),body fat:10.8%±4.5%).For each athlete,prior to cardiopulmonary exercise testing(CPET),body composition,spirometry,and lactate blood levels,were recorded.Differences between groups were assessed with the independent samples t-test(p<0.05).Several differences were detected between the two groups:ventilation(:Resting:[14.7±3.1]L·min^(−1)vs.[11.5±2.6]L·min^(−1),p=0.001;Maximal Effort:[137.1±15.5]L·min^(−1)vs.[109.1±18.4]L·min^(−1),p<0.001),ratio VE/maximal voluntary ventilation(Resting:7.9%±1.8%vs.5.7%±1.7%,p<0.001;Maximal Effort:73.7%±10.8%vs.63.1%±9.0%,p=0.002),ratioVE/BSA(Resting:7.9%±2.0%vs.5.9%±1.4%,p=0.001;Maximal Effort:73.7%±11.1%vs.66.2%±9.2%,p=0.026),heart rate(Maximal Effort:[191.6±7.8]bpm vs.[196.6±8.6]bpm,p=0.041),and lactate acid(Resting:[1.8±0.8]mmol·L^(−1)vs.[0.9±0.1]mmol·L^(−1),p<0.001;Maximal Effort:[11.0±1.6]mmol·L^(−1)vs.[9.8±1.2]mmol·L^(−1),p=0.009),during CPET.No significant differences were identified regarding maximal oxygen uptake([55.7±4.4]ml·min^(−1)·kg−1 vs.[55.4±4.6]ml·min^(−1)·kg−1,p=0.831).Our findings demonstrate a pattern of compromised respiratory function in post-COVID-19 athletes characterized by increased respiratory work at both rest and maximum effort as well as hyperventilation during exercise,which may explain the reported increased metabolic needs. 展开更多
关键词 Cardiopulmonary exercise testing Infected with COVID-19 Respiratory work
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部