Active ingredients fatty acids as antibacterial agent from the brown algae Padina pavonica and Hormophysa triquetra

Objective:To estimate the fatty acids content in the brown algae Padina pavonica(P.pavonica)and Hormophysa triquetra(H.triquetra)and evaluate their potential antimicrobial activity as bioactive compounds.Methods:The fatty acid compositions of the examined species were analyzed using gas chromatography-mass spectrometry.The antimicrobial activity of crude and fatty acids was assessed using the agar plug technique.Results:The fatty acids profile ranged from C8:0 to C20:4.Concentration of saturated fatty acids in P.pavonica was in the order palmitic>myristic>stearic whereas concentration of the unsaturated fatty acids was oleic acid>palmitoleic>9-cis-hexadecenoic>linoleic acid>α-linolenic>arachidonic>elaidic acid.H.triquetra contained high concentration of saturated fatty acids than those of P.pavonica which was in the order as follows:palmitic>margaric>myristic>nonadecyclic>stearic>caprylic>tridecylic>pentadecylic>lauric while the unsaturated fatty acids consisted of oleic>nonadecenoic>non adecadienoate>margaroleic.The crude and fatty acid extracts of H.triquetra and P.pavonica were biologically active on the tested pathogens.H.triquetra exhibited a larger inhibitory zone than P.pavonica.Conclusions:The brown algae P.pavonica and H.triquetra have high efficient amount of fatty acids and showed strong antibacterial activity,especially H.triquetra.