Multi-component flow with chemical reactions is a common problem in different industrial applications:the mixing chamber of a reaction injection molding(RIM)machine;the dynamics of diesel soot particles interacting wi...Multi-component flow with chemical reactions is a common problem in different industrial applications:the mixing chamber of a reaction injection molding(RIM)machine;the dynamics of diesel soot particles interacting with a porous-ceramic particulate filter;reactive transport in porous media;bio-chemical processes involving enzyme-catalyzed kinetics.In all these cases,mass diffusion/convection and wall or volume chemical interactions among components play an important role.In the present paper we underline the importance of diffusion/convection/reaction mechanisms in bio-chemical processes using the Lattice Boltzmann(LB)technique.The bio-application where we studied diffusion/convection/reaction mechanisms is the quorum-sensing pathway for the bio-synthesis of the AI-2,a molecule that allows the bacteria to launch a coordinated attack on a host immune system(see[9,10]for more details of the bio-application).The overall goal is to create a micro-device to screen potential drugs that inhibit AI-2 bio-synthesis.The Michaelis-Menten saturation kinetic model is implemented at the reactive surface and the results are shown in terms of two dimensionless numbers:Damkohler(Da)and Peclet(Pe)number.For high Pe number a small conversion of reactants into products is obtained at the reactive surface,but the overall flux of products is high;moreover,a fast saturation of the conversion of reactants to products is obtained for high Da numbers.The trade-off for setting the Pe and Da numbers depends on the specific application and the technologies used in the micro-device(e.g.,sensitivity of the detector,cost of reactants).展开更多
文摘Multi-component flow with chemical reactions is a common problem in different industrial applications:the mixing chamber of a reaction injection molding(RIM)machine;the dynamics of diesel soot particles interacting with a porous-ceramic particulate filter;reactive transport in porous media;bio-chemical processes involving enzyme-catalyzed kinetics.In all these cases,mass diffusion/convection and wall or volume chemical interactions among components play an important role.In the present paper we underline the importance of diffusion/convection/reaction mechanisms in bio-chemical processes using the Lattice Boltzmann(LB)technique.The bio-application where we studied diffusion/convection/reaction mechanisms is the quorum-sensing pathway for the bio-synthesis of the AI-2,a molecule that allows the bacteria to launch a coordinated attack on a host immune system(see[9,10]for more details of the bio-application).The overall goal is to create a micro-device to screen potential drugs that inhibit AI-2 bio-synthesis.The Michaelis-Menten saturation kinetic model is implemented at the reactive surface and the results are shown in terms of two dimensionless numbers:Damkohler(Da)and Peclet(Pe)number.For high Pe number a small conversion of reactants into products is obtained at the reactive surface,but the overall flux of products is high;moreover,a fast saturation of the conversion of reactants to products is obtained for high Da numbers.The trade-off for setting the Pe and Da numbers depends on the specific application and the technologies used in the micro-device(e.g.,sensitivity of the detector,cost of reactants).
