<strong>Background:</strong><span style="font-family:Verdana;"> The SARS-CoV-2 and associated corona virus disease COVID-19</span><span style="font-family:Verdana;"> h...<strong>Background:</strong><span style="font-family:Verdana;"> The SARS-CoV-2 and associated corona virus disease COVID-19</span><span style="font-family:Verdana;"> ha</span><span style="font-family:Verdana;">ve</span><span style="font-family:Verdana;"> been declared a pandemic having a poor prognosis among individuals with debilitating conditions and those who are immune</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">compromised. Current evidence is however limited on maternal and fetal transmission and pregnancy outcomes. We aimed to describe the pattern of SARS-CoV-2 infection and outcomes in a group of pregnant women followed</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">up at a tertiary care unit in Cameroon. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">This was an observational study conducted over a period of 3 months (April 1</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">to June 30, 2020) at the Yaounde Central Hospital. All pregnant women who were tested positive for SARS-CoV-2 and who provided a signed written informed consent were included in the study. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Out of 83 pregnant women who presented with symptoms suspicious of COVID-19, 25 were tested positive. The median age of these women was 31 (27 </span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 35)</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">years. A total of 76% consulted within 6 days of onset of symptoms and 68% had a gestational age greater than 28 weeks. The most comm</span><span style="font-family:Verdana;">on </span><span style="font-family:Verdana;">presenting complaint was fever (88%). All 25 pregnant women who </span></span><span style="font-family:Verdana;">were </span><span style="font-family:Verdana;">tested posit</span><span style="font-family:Verdana;">i</span><span style="font-family:Verdana;">ve for COVID-19 were followed up with 9/25 deliveries registered. There were two intra-uterine f</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;">tal death</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> and seven live births. All the live birth babies </span><span style="font-family:Verdana;">were </span><span style="font-family:""><span style="font-family:Verdana;">tested negative on Real Time-Polymerase Chain Reaction (RT-PCR) testing which was performed after birth. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Deliverance of live and SARS-CoV-2 negative babies from COVID-19 pregnant women is possible.</span></span>展开更多
文摘<strong>Background:</strong><span style="font-family:Verdana;"> The SARS-CoV-2 and associated corona virus disease COVID-19</span><span style="font-family:Verdana;"> ha</span><span style="font-family:Verdana;">ve</span><span style="font-family:Verdana;"> been declared a pandemic having a poor prognosis among individuals with debilitating conditions and those who are immune</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">compromised. Current evidence is however limited on maternal and fetal transmission and pregnancy outcomes. We aimed to describe the pattern of SARS-CoV-2 infection and outcomes in a group of pregnant women followed</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">up at a tertiary care unit in Cameroon. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">This was an observational study conducted over a period of 3 months (April 1</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">to June 30, 2020) at the Yaounde Central Hospital. All pregnant women who were tested positive for SARS-CoV-2 and who provided a signed written informed consent were included in the study. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Out of 83 pregnant women who presented with symptoms suspicious of COVID-19, 25 were tested positive. The median age of these women was 31 (27 </span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 35)</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">years. A total of 76% consulted within 6 days of onset of symptoms and 68% had a gestational age greater than 28 weeks. The most comm</span><span style="font-family:Verdana;">on </span><span style="font-family:Verdana;">presenting complaint was fever (88%). All 25 pregnant women who </span></span><span style="font-family:Verdana;">were </span><span style="font-family:Verdana;">tested posit</span><span style="font-family:Verdana;">i</span><span style="font-family:Verdana;">ve for COVID-19 were followed up with 9/25 deliveries registered. There were two intra-uterine f</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;">tal death</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> and seven live births. All the live birth babies </span><span style="font-family:Verdana;">were </span><span style="font-family:""><span style="font-family:Verdana;">tested negative on Real Time-Polymerase Chain Reaction (RT-PCR) testing which was performed after birth. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Deliverance of live and SARS-CoV-2 negative babies from COVID-19 pregnant women is possible.</span></span>