Congenital heart disease(CHD)is the commonest birth defect,affecting approximately 9.4/1000 live births.^(1)Atrial Septal Defect(ASD)is one of the commonest CHD clinical phenotypes,which frequently requires treatment ...Congenital heart disease(CHD)is the commonest birth defect,affecting approximately 9.4/1000 live births.^(1)Atrial Septal Defect(ASD)is one of the commonest CHD clinical phenotypes,which frequently requires treatment either in childhood or adulthood,and can lead to severe complications such as right heart failure and cardiac arrhythmia.Previous genome-wide association studies(GWAS)have identified a region of chromosome 4p16(Ch4p16)associated with the risk of ASD.展开更多
基金supported by The University of Manchester-Peking University Health Science Centre Alliance,the China Scholarships Council,and British Heart Foundation Programme Grant RG/15/12/31616.
文摘Congenital heart disease(CHD)is the commonest birth defect,affecting approximately 9.4/1000 live births.^(1)Atrial Septal Defect(ASD)is one of the commonest CHD clinical phenotypes,which frequently requires treatment either in childhood or adulthood,and can lead to severe complications such as right heart failure and cardiac arrhythmia.Previous genome-wide association studies(GWAS)have identified a region of chromosome 4p16(Ch4p16)associated with the risk of ASD.
