AIM: To investigate the impact of spleen operation (SO) on interferon-α (IFN-α)-based antiviral treatment in patients with hepatitis C virus (HCV)-related cirrhosis.
The prediction of long term failure behaviors and lifetime of aged glass polymers from the short term tests of reduced rupture creep compliance (or strain) is one of difficult problems in polymer science and enginee...The prediction of long term failure behaviors and lifetime of aged glass polymers from the short term tests of reduced rupture creep compliance (or strain) is one of difficult problems in polymer science and engineering. A new "universal reduced rupture creep approach" with exact theoretical analysis and computations is proposed in this work. Failure by creep for polymeric material is an important problem to be addressed in the engineering. A universal equation on reduced extensional failure creep compliance for PMMA has been derived. It is successful in relating the reduced extensional failure creep compliance with aging time, temperature, levels of stress, the average growth dimensional number and the parameter in K-W-W function. Based on the universal equation, a method for the prediction of failure behavior, failure strain criterion, failure time of PMMA has been developed which is named as a universal "reduced rupture creep approach". The results show that the predicted failure strain and failure time of PMMA at different aging times for different levels of stress are all in agreement with those obtained directly from experiments, and the proposed method is reliable and practical. The dependences of reduced extensional failure creep compliance on the conditions of aging time, failure creep stress, the structure of fluidized-domain constituent chains are discussed. The shifting factor, exponent for time-stress superposition at different levels of stress and the shifting factor, exponent for time-time aging superposition at different aging time are theoretically defined respectively.展开更多
基金Supported by National S and T Major Project for Infectious Diseases Control,No.2012ZX10002-003National Major S and T Special Project for"Significant New Drugs Development",No.2012ZX09303-019Beijing Natural Science Foundation,No.7122191
文摘AIM: To investigate the impact of spleen operation (SO) on interferon-α (IFN-α)-based antiviral treatment in patients with hepatitis C virus (HCV)-related cirrhosis.
文摘The prediction of long term failure behaviors and lifetime of aged glass polymers from the short term tests of reduced rupture creep compliance (or strain) is one of difficult problems in polymer science and engineering. A new "universal reduced rupture creep approach" with exact theoretical analysis and computations is proposed in this work. Failure by creep for polymeric material is an important problem to be addressed in the engineering. A universal equation on reduced extensional failure creep compliance for PMMA has been derived. It is successful in relating the reduced extensional failure creep compliance with aging time, temperature, levels of stress, the average growth dimensional number and the parameter in K-W-W function. Based on the universal equation, a method for the prediction of failure behavior, failure strain criterion, failure time of PMMA has been developed which is named as a universal "reduced rupture creep approach". The results show that the predicted failure strain and failure time of PMMA at different aging times for different levels of stress are all in agreement with those obtained directly from experiments, and the proposed method is reliable and practical. The dependences of reduced extensional failure creep compliance on the conditions of aging time, failure creep stress, the structure of fluidized-domain constituent chains are discussed. The shifting factor, exponent for time-stress superposition at different levels of stress and the shifting factor, exponent for time-time aging superposition at different aging time are theoretically defined respectively.