A copper-catalyzed stereoselective 1,3-dipolar cycloaddition of methyleneindolinones and N,N0-cyclic azomethine imines has been developed under mild reaction conditions.The spiro[pyrazolidin-3,30-oxindoles] were obtai...A copper-catalyzed stereoselective 1,3-dipolar cycloaddition of methyleneindolinones and N,N0-cyclic azomethine imines has been developed under mild reaction conditions.The spiro[pyrazolidin-3,30-oxindoles] were obtained in moderate to high isolated yields（up to 82%） with good stereoselevtivities（up to 15：1） in the presence of 5 mol% of Cu（OAc）2at room temperature.展开更多
基金the National Natural Science Foundation of China (No.21172023)Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) and STD of Jiangsu Province for their financial supports
文摘A copper-catalyzed stereoselective 1,3-dipolar cycloaddition of methyleneindolinones and N,N0-cyclic azomethine imines has been developed under mild reaction conditions.The spiro[pyrazolidin-3,30-oxindoles] were obtained in moderate to high isolated yields（up to 82%） with good stereoselevtivities（up to 15：1） in the presence of 5 mol% of Cu（OAc）2at room temperature.
