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Milligan-Morgan hemorrhoidectomy with anal cushion suspension and partial internal sphincter resection for circumferential mixed hemorrhoids 被引量:44
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作者 Ming Lu guang-ying shi +3 位作者 Guo-Qiang Wang Yan Wu Yang Liu Hao Wen 《World Journal of Gastroenterology》 SCIE CAS 2013年第30期5011-5015,共5页
AIM:To identify a more effective treatment protocol for circumferential mixed hemorrhoids.METHODS:A total of 192 patients with circumferential mixed hemorrhoids were randomized into the treatment group,where they unde... AIM:To identify a more effective treatment protocol for circumferential mixed hemorrhoids.METHODS:A total of 192 patients with circumferential mixed hemorrhoids were randomized into the treatment group,where they underwent Milligan-Morgan hemorrhoidectomy with anal cushion suspension and partial internal sphincter resection,or the control group,where traditional external dissection and internal ligation were performed.Postoperative recovery and complications were monitored.RESULTS:The time to wound healing was 12.96 ± 2.25 d in the treatment group shorter than 19.58 ± 2.71 d in the control group.Slight pain rate was 58.3% in the treatment group higher than 22.9% in the control group;moderate pain rate was 33.3% in the treatment group lower than 56.3% in the control group severe pain rate was 8.4% in the treatment group lower than 20.8% in the control group.No edema rate was 70.8% in the treatment group higher than 43.8% in the control group;mild local edema rate was 26% in the treatment group lower than 39.6% in the control group obvious local edema was 3.03% in the treatment group lower than 16.7% in the control group.No stenosis rate was 85.4% in the treatment group higher than 63.5% in the control group;moderate stenosis rate was 14.6% in the treatment group Lower than 27.1% in the control group severe anal stenosis rate was 0% in the treatment group lower than 9.4% in the control group.CONCLUSION:Milligan-Morgan hemorrhoidectomy with anal cushion suspension and partial internal sphincter resection is the optimal treatment for circumferential mixed hemorrhoids and can be widely applied in clinical settings. 展开更多
关键词 MILLIGAN-MORGAN HEMORRHOIDECTOMY Mixed HEMORRHOIDS ANAL CUSHION Internal SPHINCTER
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原发性肝癌合并糖尿病患者血清胰岛素样生长因子1水平及临床意义
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作者 石光英 孙昱 +1 位作者 梁星辰 谢敬东 《世界华人消化杂志》 CAS 2021年第5期236-241,共6页
背景在单纯原发性肝癌和2型糖尿病患者血清中研究结果报告称有血清胰岛素样生长因子1(insulin like growth factor 1,IGF-1)水平下降,但是也有报道称其升高的情况,观察原发性肝癌和2型糖尿病是否有相互促进作用,进而评估血清IGF-1对该... 背景在单纯原发性肝癌和2型糖尿病患者血清中研究结果报告称有血清胰岛素样生长因子1(insulin like growth factor 1,IGF-1)水平下降,但是也有报道称其升高的情况,观察原发性肝癌和2型糖尿病是否有相互促进作用,进而评估血清IGF-1对该类患者的预后影响,以期根据血清中IGF-1水平早期发现肝癌提供理论依据,为肝癌合并2型糖尿病的早期治疗以及预防提供有力支持,这对肝癌患者的有效防治及尽可能的延长其生存时间具有重要的科学价值及社会意义.目的探究IGF-1在原发性肝癌合并2型糖尿病患者中的表达及其临床意义.方法选取2014-2018年新疆生产建设兵团医院、新疆医学院、昌吉州医院糖尿病患者80例、原发性肝癌患者80例及原发性肝癌合并2型糖尿病患者80例,入院或门诊检测患者IGF-1、甲胎蛋白(a-feto-protein,AFP)和糖类抗原199(carbohydrate antigen 199,CA199)水平.结果3组患者IGF-1、AFP、CA199比较,差异均有统计学意义.其中,糖尿病患者组、原发性肝癌合并2型糖尿病患者组的IGF-1高于原发性肝癌患者组;原发性肝癌合并2型糖尿病患者组、原发性肝癌组的AFP和CA199高于糖尿病组.不同分期的原发性肝癌组患者IGF-1、AFP和CA199比较,差异无明显统计学意义.不同分期的原发性肝癌合并糖尿病组患者IGF-1、AFP和CA199比较,差异无明显统计学意义.结论原发性肝癌合并2型糖尿病患者组的IGF-1较原发性肝癌组升高,或可用于指导原发性肝癌合并2型糖尿病人群肿瘤的早期筛查.但是具体的检测数值指标尚不明确,拟在后续研究中深入开展相关课题研究. 展开更多
关键词 原发性肝癌 2型糖尿病 血清胰岛素样生长因子1
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