BACKGROUND Pipeline dredging agents are new household deep cleaning products used to dredge blockages in kitchen and bathroom pipeline caused by grease,hair,vegetable residue,paper cotton fibre,and other organic subst...BACKGROUND Pipeline dredging agents are new household deep cleaning products used to dredge blockages in kitchen and bathroom pipeline caused by grease,hair,vegetable residue,paper cotton fibre,and other organic substances.Pipeline dredging agents are corrosive chemicals that can cause poisoning through corrosive damage to the digestive tract;however,this has not been reported clinically.Therefore,this report emphasises that oral pipeline dredging agent poisoning can cause corrosive damage to the digestive tract and may have serious health consequences.CASE SUMMARY A 68-year-old man consumed liquor(200 m L) at approximately 13:00 on April 22,2021.At approximately 16:00,his family found him unresponsive with blackened lips,blood spots in the corners of the mouth,and blood stains on the ground,as well as an empty bottle of a pipeline dredging agent.One hour later,he was admitted to the emergency department of a local hospital.Considering the empty bottle,he was suspected to have sustained severe corrosive damage to the digestive tract and was transferred to our department at 23:15 on April 22,2021.He developed dysphagia and intermittent fever and experienced difficulty in opening his mouth throughout his hospital stay.The patient’s condition gradually stabilised.However,he suddenly developed respiratory failure on day 12,and endotracheal intubation and ventilator-assisted ventilation were performed.However,the patient died after 1.5 h despite emergency rescue efforts.CONCLUSION Pipeline dredging agents are highly corrosive and may cause corrosive damage to the digestive tract and asphyxia upon consumption.展开更多
Dear editor,Dimethylamine borane(DMAB,CAS no.74-94-2),also called boron-dimethylamine complex,is a white crystalline solid.It has an amine odour under mild conditions.[1]As an excellent reducing agent,DMAB is widely u...Dear editor,Dimethylamine borane(DMAB,CAS no.74-94-2),also called boron-dimethylamine complex,is a white crystalline solid.It has an amine odour under mild conditions.[1]As an excellent reducing agent,DMAB is widely used in the semiconductor industry,pharmaceutical manufacturing,[2]oligomer and polymer production,and hydrogen storage.[3]Acute DMAB exposure may cause eye or respiratory irritation,throat discomfort,vomiting,diarrhoea,and pulmonary oedema.[1,4]Isolated reports indicated that DMAB exposure causes acute cerebellar oedema and peripheral neuropathy.[1,5,6]Herein,we report a case of DMAB poisoning via dermal absorption in which the central and peripheral nervous systems were the primary sites of toxic injury.We highlight the use of brain magnetic resonance imaging(MRI)and electromyography(EMG)for evaluation after exposure.展开更多
Dear editor,University laboratory-related events include fire,explosion,chemical gas leakage,poisoning related to the loss of toxic reagents,specific pathogen infection,leakage of radioactive material,etc.[1]Chlorofor...Dear editor,University laboratory-related events include fire,explosion,chemical gas leakage,poisoning related to the loss of toxic reagents,specific pathogen infection,leakage of radioactive material,etc.[1]Chloroform is an important material used frequently in the laboratory,for organic synthesis or used as an organic glass binder and organic matter extractor.[2]As a widely used anesthetic in clinics in the 1950s and the 1960s,[3]chloroform was abandoned because of hepatorenal toxicity.We report a case of a 24-year-old suicidal female student with chloroform poisoning.展开更多
文摘BACKGROUND Pipeline dredging agents are new household deep cleaning products used to dredge blockages in kitchen and bathroom pipeline caused by grease,hair,vegetable residue,paper cotton fibre,and other organic substances.Pipeline dredging agents are corrosive chemicals that can cause poisoning through corrosive damage to the digestive tract;however,this has not been reported clinically.Therefore,this report emphasises that oral pipeline dredging agent poisoning can cause corrosive damage to the digestive tract and may have serious health consequences.CASE SUMMARY A 68-year-old man consumed liquor(200 m L) at approximately 13:00 on April 22,2021.At approximately 16:00,his family found him unresponsive with blackened lips,blood spots in the corners of the mouth,and blood stains on the ground,as well as an empty bottle of a pipeline dredging agent.One hour later,he was admitted to the emergency department of a local hospital.Considering the empty bottle,he was suspected to have sustained severe corrosive damage to the digestive tract and was transferred to our department at 23:15 on April 22,2021.He developed dysphagia and intermittent fever and experienced difficulty in opening his mouth throughout his hospital stay.The patient’s condition gradually stabilised.However,he suddenly developed respiratory failure on day 12,and endotracheal intubation and ventilator-assisted ventilation were performed.However,the patient died after 1.5 h despite emergency rescue efforts.CONCLUSION Pipeline dredging agents are highly corrosive and may cause corrosive damage to the digestive tract and asphyxia upon consumption.
基金Scientific Research Project of Qilu Hospital,Shandong University(project no.KYLL-2019-296).
文摘Dear editor,Dimethylamine borane(DMAB,CAS no.74-94-2),also called boron-dimethylamine complex,is a white crystalline solid.It has an amine odour under mild conditions.[1]As an excellent reducing agent,DMAB is widely used in the semiconductor industry,pharmaceutical manufacturing,[2]oligomer and polymer production,and hydrogen storage.[3]Acute DMAB exposure may cause eye or respiratory irritation,throat discomfort,vomiting,diarrhoea,and pulmonary oedema.[1,4]Isolated reports indicated that DMAB exposure causes acute cerebellar oedema and peripheral neuropathy.[1,5,6]Herein,we report a case of DMAB poisoning via dermal absorption in which the central and peripheral nervous systems were the primary sites of toxic injury.We highlight the use of brain magnetic resonance imaging(MRI)and electromyography(EMG)for evaluation after exposure.
文摘Dear editor,University laboratory-related events include fire,explosion,chemical gas leakage,poisoning related to the loss of toxic reagents,specific pathogen infection,leakage of radioactive material,etc.[1]Chloroform is an important material used frequently in the laboratory,for organic synthesis or used as an organic glass binder and organic matter extractor.[2]As a widely used anesthetic in clinics in the 1950s and the 1960s,[3]chloroform was abandoned because of hepatorenal toxicity.We report a case of a 24-year-old suicidal female student with chloroform poisoning.
