A rhodium-catalyzed dearomative rearrangement reaction of 2-oxypyridines has been developed by using cyclopropenes as carbene precursors.This protocol features broad substrate scope and mild reac-tion conditions,provi...A rhodium-catalyzed dearomative rearrangement reaction of 2-oxypyridines has been developed by using cyclopropenes as carbene precursors.This protocol features broad substrate scope and mild reac-tion conditions,providing a reliable and practical approach for the highly efficient synthesis of 2-alkylated 2-pyridone derivatives from readily available O-substituted pyridine compounds.展开更多
基金We gratefully acknowledge the National Natural Science Foundation of China(21971026 and 22171028)Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology(BM2012110)for their financial support.
文摘A rhodium-catalyzed dearomative rearrangement reaction of 2-oxypyridines has been developed by using cyclopropenes as carbene precursors.This protocol features broad substrate scope and mild reac-tion conditions,providing a reliable and practical approach for the highly efficient synthesis of 2-alkylated 2-pyridone derivatives from readily available O-substituted pyridine compounds.
