This study was conducted to analyze and summaries the current situation of acupuncture post-operative consultation of pancreatic cancer patients in the Qilu hospital of Shandong University,further provide a reference ...This study was conducted to analyze and summaries the current situation of acupuncture post-operative consultation of pancreatic cancer patients in the Qilu hospital of Shandong University,further provide a reference for acupuncture treatment of post-operative complications after pancreatic surgery,especially the effect of acupuncture in treating gastrointestinal dysfunction after pancreatic surgery.The consultation reasons,diagnosis,treatments,patient compliance,and the effect of acupuncture treatment of post-operative was studied and analyzed in 128 cases from October 9,2020 to October 9,2021.A total of 128 patients was selected for this study,and 116 of the patients were completely treated.This study showed that the effective rate of acupuncture;For early post-operative inflammatory bowel obstruction was 94.85%;For post-operative gastric emptying dysfunction was 81.25%;For early post-operative inflammatory bowel obstruction with gastric emptying disorder was 66.67%;and Clinical total effective rate was 91.38%.This study concluded that acupuncture may promote pancreatic gastrointestinal function rehabilitation,and provide a new method to enhance the patient’s recovery after surgery.展开更多
This work was supported by the National Key Research and Development Program of China(2022YFC3500401),the National Natural Science Foundation of China(No.82205250)and the Natural Science Foundation of Shandong Provinc...This work was supported by the National Key Research and Development Program of China(2022YFC3500401),the National Natural Science Foundation of China(No.82205250)and the Natural Science Foundation of Shandong Province,China(No.ZR2021QH056).展开更多
Background:Electroacupuncture(EA)therapy,as a combination of electric stimulation and traditional acupunc-ture technology,is currently an important mean for treatment of ischemic stroke and post-stroke rehabilitation ...Background:Electroacupuncture(EA)therapy,as a combination of electric stimulation and traditional acupunc-ture technology,is currently an important mean for treatment of ischemic stroke and post-stroke rehabilitation in China.Because of its remarkable therapeutic effect,it has been widely used in hospitals and clinic,however,the detailed mechanism remains unclear.Objective:This research aims to comprehensively and systematically elucidate the mechanisms of EA treatment at the acupoints of Zusanli(ST36)and Baihui(GV20)on ischemic stroke.Methods:In this study,EA was performed twice at onset of reperfusion and 20 h after reperfusion following cerebral ischemia-reperfusion(I/R)in middle cerebral artery occlusion(MCAO)rats,and transcriptomic changes of various molecules in ischemic hippocampal neurons of rats in Sham,I/R and EA groups were detected by RNA-Sequencing(RNA-Seq).Results:Thus,we detected 18 significantly different genes related to atherosclerosis(AS),with their functions associated with lipid metabolism,thrombosis,monocytes and vascular smooth muscle cells.And,we detected 10 significantly different genes related to oxidative stress and apoptosis and 10 significantly different genes related to calcium overload and excitatory amino acids release.Also,we detected 19 significantly different genes related to blood-brain barrier(BBB)and 22 significantly different genes related to inflammatory response.Conclusion:In conclusion,EA can play a role in treating ischemic stroke through a variety of mechanisms,affecting atherosclerosis,oxidative stress,apoptosis,calcium overload,excitatory amino acids release,blood-brain barrier(BBB)and inflammatory response.展开更多
文摘This study was conducted to analyze and summaries the current situation of acupuncture post-operative consultation of pancreatic cancer patients in the Qilu hospital of Shandong University,further provide a reference for acupuncture treatment of post-operative complications after pancreatic surgery,especially the effect of acupuncture in treating gastrointestinal dysfunction after pancreatic surgery.The consultation reasons,diagnosis,treatments,patient compliance,and the effect of acupuncture treatment of post-operative was studied and analyzed in 128 cases from October 9,2020 to October 9,2021.A total of 128 patients was selected for this study,and 116 of the patients were completely treated.This study showed that the effective rate of acupuncture;For early post-operative inflammatory bowel obstruction was 94.85%;For post-operative gastric emptying dysfunction was 81.25%;For early post-operative inflammatory bowel obstruction with gastric emptying disorder was 66.67%;and Clinical total effective rate was 91.38%.This study concluded that acupuncture may promote pancreatic gastrointestinal function rehabilitation,and provide a new method to enhance the patient’s recovery after surgery.
基金supported by the National Key Research and Development Program of China(2022YFC3500401)the National Natural Scence Foundation of China(No.82205250)the Natural Science Foundation of Shandong Province,China(No.ZR2021QH056).
文摘This work was supported by the National Key Research and Development Program of China(2022YFC3500401),the National Natural Science Foundation of China(No.82205250)and the Natural Science Foundation of Shandong Province,China(No.ZR2021QH056).
基金supported by the National Natural Science Foundation of China(No.82205250)the Natural Science Foundation of Shan-dong Province,China(No.ZR2021QH056)。
文摘Background:Electroacupuncture(EA)therapy,as a combination of electric stimulation and traditional acupunc-ture technology,is currently an important mean for treatment of ischemic stroke and post-stroke rehabilitation in China.Because of its remarkable therapeutic effect,it has been widely used in hospitals and clinic,however,the detailed mechanism remains unclear.Objective:This research aims to comprehensively and systematically elucidate the mechanisms of EA treatment at the acupoints of Zusanli(ST36)and Baihui(GV20)on ischemic stroke.Methods:In this study,EA was performed twice at onset of reperfusion and 20 h after reperfusion following cerebral ischemia-reperfusion(I/R)in middle cerebral artery occlusion(MCAO)rats,and transcriptomic changes of various molecules in ischemic hippocampal neurons of rats in Sham,I/R and EA groups were detected by RNA-Sequencing(RNA-Seq).Results:Thus,we detected 18 significantly different genes related to atherosclerosis(AS),with their functions associated with lipid metabolism,thrombosis,monocytes and vascular smooth muscle cells.And,we detected 10 significantly different genes related to oxidative stress and apoptosis and 10 significantly different genes related to calcium overload and excitatory amino acids release.Also,we detected 19 significantly different genes related to blood-brain barrier(BBB)and 22 significantly different genes related to inflammatory response.Conclusion:In conclusion,EA can play a role in treating ischemic stroke through a variety of mechanisms,affecting atherosclerosis,oxidative stress,apoptosis,calcium overload,excitatory amino acids release,blood-brain barrier(BBB)and inflammatory response.