Background: Distinguishing chronic telogen effluvium (CTE)-from androgenetic alopecia (AGA) may be difficult especially when associated in the same patient. Observations: One hundred consecutive patients with hair los...Background: Distinguishing chronic telogen effluvium (CTE)-from androgenetic alopecia (AGA) may be difficult especially when associated in the same patient. Observations: One hundred consecutive patients with hair loss who were clinicall y diagnosed as havingCTE, AGA, AGA+CTE, or remitting CTE. Patients washed their hair in the sink in a standardized way. All shed hairs were counted and divided “blindly”into 5 cm or longer, intermediate length (>3 to < 5 cm), and 3 cm or shorter. The latter were considered telogen vellus hairs, and patients having a t least 10%of them were classified as having AGA.We assumed that patients shedd ing 200 hairs ormore had CTE. The κstatistic revealed, however, that the best c oncordance between clinical and numerical diagnosis (κ=0.527)was obtained by se tting the cutoff shedding value at 100 hairs or more. Of the 100 patients, 18 wi th 10%or more of hairs that were 3 cm or shorter and who shed fewer than 100 ha irs were diagnosed as having AGA; 34 with fewer than 10%of hairs that were 3 cm or shorter and who shed at least 100 hairs were diagnosed as having CTE; 34 wit h 10%or more of hairs that were 3 cm or shorter and who shed at least 100 hairs were diagnosed as having AGA +CTE; and 14 with fewer than 10%of hairs that we re 3 cm or shorter and who shed fewer than 100 hairs were diagnosed as having CT E in remission. Conclusion: This method is simple, noninvasive, and suitable for office evaluation .展开更多
文摘Background: Distinguishing chronic telogen effluvium (CTE)-from androgenetic alopecia (AGA) may be difficult especially when associated in the same patient. Observations: One hundred consecutive patients with hair loss who were clinicall y diagnosed as havingCTE, AGA, AGA+CTE, or remitting CTE. Patients washed their hair in the sink in a standardized way. All shed hairs were counted and divided “blindly”into 5 cm or longer, intermediate length (>3 to < 5 cm), and 3 cm or shorter. The latter were considered telogen vellus hairs, and patients having a t least 10%of them were classified as having AGA.We assumed that patients shedd ing 200 hairs ormore had CTE. The κstatistic revealed, however, that the best c oncordance between clinical and numerical diagnosis (κ=0.527)was obtained by se tting the cutoff shedding value at 100 hairs or more. Of the 100 patients, 18 wi th 10%or more of hairs that were 3 cm or shorter and who shed fewer than 100 ha irs were diagnosed as having AGA; 34 with fewer than 10%of hairs that were 3 cm or shorter and who shed at least 100 hairs were diagnosed as having CTE; 34 wit h 10%or more of hairs that were 3 cm or shorter and who shed at least 100 hairs were diagnosed as having AGA +CTE; and 14 with fewer than 10%of hairs that we re 3 cm or shorter and who shed fewer than 100 hairs were diagnosed as having CT E in remission. Conclusion: This method is simple, noninvasive, and suitable for office evaluation .
