In Issue 1 of this special topic series on Reproductive hnmunology （September 2014 issue of Cellular and MolecMar Immunology, Vol. 11, No. 5）, immune cell populations in the reproductive tracts of males and non-preg...In Issue 1 of this special topic series on Reproductive hnmunology （September 2014 issue of Cellular and MolecMar Immunology, Vol. 11, No. 5）, immune cell populations in the reproductive tracts of males and non-pregnant females were discussed. Emphasis was placed on endocrine regulation of the specialized cells that populate these mucosal tissues.展开更多
It is estimated that immune system evolution commenced more than 600 million years ago （Mya） when ancestral forms of MHC and CD45 appeared establishing innate immunity. By 500 Mya, RAG gene evolution had occurred, f...It is estimated that immune system evolution commenced more than 600 million years ago （Mya） when ancestral forms of MHC and CD45 appeared establishing innate immunity. By 500 Mya, RAG gene evolution had occurred, founding adaptive immunity.The first mammals appeared much later （220 Mya） and reproduced by laying of eggs. Placental mammals with internal gestations and live born offspring have existed for only 100 Mya, with humans and mice being relatively recent mam- malian evolutions.展开更多
文摘In Issue 1 of this special topic series on Reproductive hnmunology （September 2014 issue of Cellular and MolecMar Immunology, Vol. 11, No. 5）, immune cell populations in the reproductive tracts of males and non-pregnant females were discussed. Emphasis was placed on endocrine regulation of the specialized cells that populate these mucosal tissues.
文摘It is estimated that immune system evolution commenced more than 600 million years ago （Mya） when ancestral forms of MHC and CD45 appeared establishing innate immunity. By 500 Mya, RAG gene evolution had occurred, founding adaptive immunity.The first mammals appeared much later （220 Mya） and reproduced by laying of eggs. Placental mammals with internal gestations and live born offspring have existed for only 100 Mya, with humans and mice being relatively recent mam- malian evolutions.
