AIM: To identify the most-cited articles in ophthalmic epidemiology over the last decade.METHODS: We performed a cited reference search on articles that were included in the ISI Web of Science database using the terms...AIM: To identify the most-cited articles in ophthalmic epidemiology over the last decade.METHODS: We performed a cited reference search on articles that were included in the ISI Web of Science database using the terms "Epidemi*" AND "ophthalm*" AND "population*" during year 2006 to 2016. TOP 100 most cited articles(T100) in ophthalmic epidemiology were short listed and analysed using bibliometrics.RESULTS: These top 100 articles in ophthalmic epidemiology were cited between 61 to 333 times. Of these T100 articles, 36% originated from United States, and 34% were published in the Ophthalmology journal. The three major topics identified were age-related macular degeneration(AMD, n=23), glaucoma(n=16) and visual impairment(n=12). The top-cited article was a study on outdoor activities and its association with the prevalence of myopia in school-aged children, published in 2008. CONCLUSION: This bibliometric analysis provides useful insights into the current development in ophthalmicepidemiology in the past decade and can help recognizing the quality of the researches, discoveries, and trends steering ophthalmic epidemiology.展开更多
A facile synthesis of suvorexant, an orexin receptor antagonist, is described. The key intermediate 6 was prepared from R-3-aminobutyric acid through protection, condensation, deprotection, cyclization, and hydrogenat...A facile synthesis of suvorexant, an orexin receptor antagonist, is described. The key intermediate 6 was prepared from R-3-aminobutyric acid through protection, condensation, deprotection, cyclization, and hydrogenation steps. The title product was obtained with a total yield of 31% （〉99% ee） after eight linear steps using commercially available raw materials.展开更多
To the Editor:Diabetic retinopathy(DR)is a condition characterized by retinal microvascular damages of diabetes mellitus.As the primary cause of blindness in adults,DR has already become a public health problem worldw...To the Editor:Diabetic retinopathy(DR)is a condition characterized by retinal microvascular damages of diabetes mellitus.As the primary cause of blindness in adults,DR has already become a public health problem worldwide and threatens the outcomes of diabetic patients and even healthy population.The correlation between DR and common anthropometric measurements represented by body mass index(BMI)was still controversial.展开更多
基金Supported by National Natural Science Foundation of China(No.81300783)Scientific Research Project of Liaoning Provincial Department of Education(No.LQNK201703)
文摘AIM: To identify the most-cited articles in ophthalmic epidemiology over the last decade.METHODS: We performed a cited reference search on articles that were included in the ISI Web of Science database using the terms "Epidemi*" AND "ophthalm*" AND "population*" during year 2006 to 2016. TOP 100 most cited articles(T100) in ophthalmic epidemiology were short listed and analysed using bibliometrics.RESULTS: These top 100 articles in ophthalmic epidemiology were cited between 61 to 333 times. Of these T100 articles, 36% originated from United States, and 34% were published in the Ophthalmology journal. The three major topics identified were age-related macular degeneration(AMD, n=23), glaucoma(n=16) and visual impairment(n=12). The top-cited article was a study on outdoor activities and its association with the prevalence of myopia in school-aged children, published in 2008. CONCLUSION: This bibliometric analysis provides useful insights into the current development in ophthalmicepidemiology in the past decade and can help recognizing the quality of the researches, discoveries, and trends steering ophthalmic epidemiology.
文摘A facile synthesis of suvorexant, an orexin receptor antagonist, is described. The key intermediate 6 was prepared from R-3-aminobutyric acid through protection, condensation, deprotection, cyclization, and hydrogenation steps. The title product was obtained with a total yield of 31% （〉99% ee） after eight linear steps using commercially available raw materials.
基金This work was supported by grants from the National Natural Science Foundation of China(No.81300783)China Postdoctoral Science Foundation(No.2019TQ0358,No.2019M661162)+1 种基金Shenyang Young and Middle-aged Science and Technology Innovation Talent Support Program(No.RC190146)Liaoning Revitalization Talents Program(No.XLYC1807082).
文摘To the Editor:Diabetic retinopathy(DR)is a condition characterized by retinal microvascular damages of diabetes mellitus.As the primary cause of blindness in adults,DR has already become a public health problem worldwide and threatens the outcomes of diabetic patients and even healthy population.The correlation between DR and common anthropometric measurements represented by body mass index(BMI)was still controversial.
