To the editor:Nurses play a vital role in healthcare by providing direct medical care to patients,and their mental well-being significantly impacts the quality of service and patient satisfaction.^(1)Ruminative thinki...To the editor:Nurses play a vital role in healthcare by providing direct medical care to patients,and their mental well-being significantly impacts the quality of service and patient satisfaction.^(1)Ruminative thinking involves repetitive thoughts about negative feelings,their causes and consequences.This common psychological behaviour innurses can significantly impact their self-evaluation and result in feelings of worthlessness.展开更多
Neuromedin B(NMB)is a member of mammalian bombesin-like peptide family and almost all its potent biological actions take place exclusively through its receptor NMBR,which has been identified as a G-protein couple rece...Neuromedin B(NMB)is a member of mammalian bombesin-like peptide family and almost all its potent biological actions take place exclusively through its receptor NMBR,which has been identified as a G-protein couple receptor with seven trans-membrane regions.NMB and NMBR represent an interesting signaling axis over which NMB/NMBR perform multiple biological activities,in particularly,they have been highlighted in the regulation of the immunology system.This review aims to provide a brief overview of the recent advancements in our understanding regarding the potential immunological functions of NMB and NMBR in cell proliferation,tumorigenesis,angiogenesis,neurogenic inflammation,anti-influenza A virus(IAV)infections,and briefly discusses the potential importance of these observations.All these implicated that targeting NMBR or developing analogues of NMB may represent a useful strategy for development of new anti-IAV agents.展开更多
基金supported by the scientific research project of Nantong Municipal Health and Wellness Commission:Construction of 4P medical management model of childhood asthma based on the cooperation of medical association(no.MA2021014).
文摘To the editor:Nurses play a vital role in healthcare by providing direct medical care to patients,and their mental well-being significantly impacts the quality of service and patient satisfaction.^(1)Ruminative thinking involves repetitive thoughts about negative feelings,their causes and consequences.This common psychological behaviour innurses can significantly impact their self-evaluation and result in feelings of worthlessness.
基金National Science Foundation of China(U1805231)National Program for Innovation and Entrepreneurship Training of University Students(202110389008)+2 种基金Special Fund Project for Scientific and Technological Innovation of Fujian Agriculture and Forestry University(CXZX2018015,CXZX2020060A)Key Laboratory Project of Animal Infectious Disease Control and Biotechnology in Fujian Province(2018KF03)National Science Foundation of Fujian Province(2020J01539).
文摘Neuromedin B(NMB)is a member of mammalian bombesin-like peptide family and almost all its potent biological actions take place exclusively through its receptor NMBR,which has been identified as a G-protein couple receptor with seven trans-membrane regions.NMB and NMBR represent an interesting signaling axis over which NMB/NMBR perform multiple biological activities,in particularly,they have been highlighted in the regulation of the immunology system.This review aims to provide a brief overview of the recent advancements in our understanding regarding the potential immunological functions of NMB and NMBR in cell proliferation,tumorigenesis,angiogenesis,neurogenic inflammation,anti-influenza A virus(IAV)infections,and briefly discusses the potential importance of these observations.All these implicated that targeting NMBR or developing analogues of NMB may represent a useful strategy for development of new anti-IAV agents.
